GLP-1 clinical trials in Massachusetts: 19 recruiting now
22 sites in 7 Massachusetts cities. Registry checked October 2, 2026.
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Weight-loss studies (5)
Weight-loss study of orforglipron
Where: Boston
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 6 to 17 with obesity.
Study record on ClinicalTrials.gov
Boston Children's Hospital, Boston
Weight-loss study of LY3305677
Where: Needham and New Bedford
What: Tests whether an investigational medicine from Lilly, LY3305677, can help people lose weight.
Free to join
Who can join: Adults 18 to 75 with obesity, BMI 27+.
Call the site: 339-793-8998Study record on ClinicalTrials.gov
Knownwell, Needham. 339-793-8998
Lucida Clinical Trials, New Bedford. 508-720-2015
Weight-loss study of tirzepatide
Where: Boston
What: Tests whether a GLP-1 and GIP medicine, tirzepatide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 27+.
Call the site: 617-726-3870Study record on ClinicalTrials.gov
Massachusetts General Hospital, Boston. 617-726-3870
Show 2 more studies
Weight-loss study of semaglutide
Where: Boston
What: Tests whether a GLP-1 medicine, semaglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity or overweight, BMI 27+.
Study record on ClinicalTrials.gov
Brigham and Women's Hospital, Boston
Weight-loss study
Where: Boston
Free to join
Who can join: Adults 18+ with obesity, BMI 25+.
Call the site: 617-726-1729Study record on ClinicalTrials.gov
Diabetes Research Center, Boston. 617-726-1729
Type 2 diabetes studies (2)
Type 2 diabetes study of semaglutide
Where: Boston
What: Tests whether a GLP-1 medicine, semaglutide, can help people with metabolic diseases lower blood sugar.
Free to join
Who can join: Adults 18 to 65 with metabolic diseases.
Call the site: 6176435419Study record on ClinicalTrials.gov
Massachusetts General Hospital, Boston. 6176435419
Type 2 diabetes study of NNC0662-0419
Where: Boston
What: Tests whether an investigational medicine from Novo Nordisk, NNC0662-0419, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes.
Study record on ClinicalTrials.gov
Brigham & Women's Hospital, Boston
Other GLP-1 studies in Massachusetts (12)
Fatty liver disease with liver scarring study of survodutide
Where: Boston
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (also called MASH or NASH) with liver scarring (fibrosis).
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Boston Medical Center, Boston. 833-602-2368
Ulcerative colitis study of tirzepatide
Where: New Bedford
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with ulcerative colitis calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with ulcerative colitis, BMI 27+.
Study record on ClinicalTrials.gov
Lucida Clinical Trials, New Bedford
Crohn's disease study of tirzepatide
Where: New Bedford
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with Crohn's disease calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with Crohn's disease, BMI 27+.
Study record on ClinicalTrials.gov
Lucida Clinical Trials, New Bedford
Show 9 more studies
Fatty liver disease (MASLD) study of retatrutide
Where: New Bedford
What: Tests whether a GLP-1, GIP and glucagon medicine from Lilly, retatrutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (MASLD), BMI 25+.
Study record on ClinicalTrials.gov
Lucida Clinical Trials, New Bedford
Prehypertension study of orforglipron
Where: Boston
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people with prediabetes lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 25+.
Call the site: 6177324245Study record on ClinicalTrials.gov
Brigham and Women's Hospital Diabetes Program, Boston. 6177324245
ASCVD study of semaglutide
Where: Boston and Worcester
What: Tests whether a GLP-1 medicine, semaglutide, can help people lower blood sugar.
Free to join
Who can join: Adults 40 to 80 with type 2 diabetes.
Call the site: 617-278-0659Study record on ClinicalTrials.gov
Brigham and Women's Hospital, Boston. 617-278-0659
UMass Chan Medical School, Worcester. 508-334-3206
Psoriasis study of tirzepatide
Where: Brighton
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people calm psoriasis.
Free to join
Who can join: Adults 18+ with psoriasis, BMI 27+.
Study record on ClinicalTrials.gov
Metro Boston Clinical Partners, Brighton
Alcohol use disorder study of tirzepatide
Where: Boston and Jamaica Plain
What: Tests whether a GLP-1 and GIP medicine, tirzepatide, can help people with alcohol use disorder drink less.
Free to join
Who can join: Adults 18+ with alcohol use disorder, BMI 23+.
Call the site: 617-732-5752Study record on ClinicalTrials.gov
Brigham and Women's Hospital, Boston
Brigham and Women's Faulkner Hospital, Jamaica Plain. 617-732-5752
Opioid use disorder study of semaglutide
Where: Fall River
What: Tests whether a GLP-1 medicine, semaglutide, can help people with opioid use disorder cut down on opioids.
Free to join
Who can join: Adults 18 to 75 with opioid use disorder, BMI 18+.
Call the site: 508-324-3522Study record on ClinicalTrials.gov
Stanley Street Treatment and Resources, Fall River. 508-324-3522
Opioid use disorder study of semaglutide
Where: Boston
What: Tests whether a GLP-1 medicine, semaglutide, can help people with opioid use disorder cut down on opioids.
Free to join
Who can join: Adults 18+ with opioid use disorder.
Call the site: 617-732-5752Study record on ClinicalTrials.gov
Brigham and Women's Hospital, Boston. 617-732-5752
Colorectal adenoma study of tirzepatide
Where: Boston
What: Tests a GLP-1 and GIP medicine, tirzepatide, in people with colorectal adenoma.
Free to join
Who can join: Adults 18 to 50 with colorectal adenoma, BMI 27+.
Call the site: 617-726-3212Study record on ClinicalTrials.gov
Massachusetts General Hospital Cancer Center, Boston. 617-726-3212
GLP-1 study
Where: Worcester
Free to join
Who can join: Adults 18+, BMI 27+.
Call the site: 617-828-8093Study record on ClinicalTrials.gov
UMass Chan Medical School - Shaw Building, Worcester. 617-828-8093
Source: ClinicalTrials.gov, the federal registry, read October 2, 2026. Open a study's registry record before you call: it can close to new participants at any time. GLP Chart does not enroll anyone, is not paid for clinical-trial referrals and has no relationship with any sponsor or site on this page.
Clinical trials by state
Every state with a GLP-1 study recruiting today. 48 of them.
- Alabama (17)
- Arizona (22)
- Arkansas (6)
- California (51)
- Colorado (17)
- Connecticut (13)
- Delaware (1)
- District of Columbia (1)
- Florida (42)
- Georgia (23)
- Hawaii (5)
- Idaho (12)
- Illinois (30)
- Indiana (19)
- Iowa (10)
- Kansas (15)
- Kentucky (15)
- Louisiana (15)
- Maine (1)
- Maryland (22)
- Massachusetts (19)
- Michigan (20)
- Minnesota (18)
- Mississippi (6)
- Missouri (21)
- Montana (3)
- Nebraska (5)
- Nevada (13)
- New Hampshire (3)
- New Jersey (12)
- New Mexico (5)
- New York (30)
- North Carolina (30)
- North Dakota (5)
- Ohio (28)
- Oklahoma (12)
- Oregon (5)
- Pennsylvania (33)
- Rhode Island (6)
- South Carolina (24)
- South Dakota (2)
- Tennessee (26)
- Texas (56)
- Utah (14)
- Virginia (28)
- Washington (23)
- West Virginia (5)
- Wisconsin (7)
