Three programs tie for the top score this month at 8.2: Mochi Health, Sesame Care and LifeMD. We break the tie on price predictability, so Mochi Health takes the number-one slot. Mochi Health holds one flat compounded price at every dose with no lock-in, the most transparent of the three, while Sesame Care runs visit-by-visit and LifeMD pairs a money-back guarantee with genuine branded Novo and Lilly supply. Any of the three is a defensible first pick.
The same compounded semaglutide runs about $149 to $299 a month across these programs, a real spread for the identical molecule before any intro pricing. Branded Wegovy and Zepbound run past $1,000 in cash.
The ranking, June 2026
Scores out of 10, equal-weighted across five dimensions. How we score
| Rank | Program | Score | This month |
|---|---|---|---|
| 1 | Mochi HealthOne flat price covers every dose, no tier jumps. | 8.2 | new |
| 2 | Sesame CarePay-per-visit care with medication sold near wholesale. | 8.2 | new |
| 3 | LifeMDBrand-name supply with an outcomes-based money-back guarantee. | 8.2 | new |
| 4 | Noom MedBehavioral program built around the medication, billed quarterly. | 8 | new |
| 5 | Henry MedsPrices show only at signup; sublingual option for needle-free. | 8 | new |
| 6 | MedviFlat refill price that holds as your dose climbs. | 7.8 | new |
| 7 | Push HealthMarketplace doctors write the script, you fill it yourself. | 7.7 | new |
| 8 | Costco / Success by SesameDiscounted member care plus brand-name medication at Costco. | 7.6 | new |
| 9 | Ro BodyPolished app with brand-name supply from the makers. | 7.5 | new |
| 10 | Ivim HealthCash for compounded, insurance route for brand-name. | 7.4 | new |
| 11 | GoodRx for Weight LossLow-cost telemedicine subscription with transparent published medication prices. | 7.4 | new |
| 12 | 9amHealthBuilt for diabetes and heart-risk patients, not weight loss alone. | 7.3 | new |
| 13 | Hone HealthMen's hormone program that pairs GLP-1 with TRT. | 7.3 | new |
| 14 | Strut HealthCompounded injectable and oral semaglutide from $149/mo published price. | 7.2 | new |
| 15 | Lemonaid HealthOne platform if you already manage other meds here. | 7.2 | new |
| 16 | Walgreens Weight ManagementBrand-name prices shown upfront, pick up at the counter. | 7.2 | new |
| 17 | Hims & HersFast async signup, brand-name only, no compounded route. | 7 | new |
| 18 | Klarity Health | 7 | new |
| 19 | KnownwellPrimary care plus obesity medicine in one insured practice. | 6.9 | new |
| 20 | FoundWidest drug catalog, but the best price needs a 12-month plan. | 6.8 | new |
| 21 | EdenAggressive intro price behind a heavier upsell flow. | 6.8 | new |
| 22 | LifeforceLongevity platform; medication priced only once you join. | 6.8 | new |
| 23 | ShedCompounded semaglutide with a weight-loss guarantee. | 6.8 | new |
| 24 | Amazon PharmacyUpfront cash prices with fast nationwide delivery. | 6.4 | new |
| 25 | CalibrateCoaching-heavy reset for insured patients who want structure. | 6.2 | new |
| 26 | Sam's Club Member HealthPill at a low member price, plus the Well health app. | 6 | new |
| 27 | WeightWatchers ClinicBehavioral framework attached, but canceling means calling support. | 5.8 | new |
How prices got here: the compounding cliff
- 2024A stable cash band. Compounded semaglutide settles around $199 to $279 a month across the early telehealth programs.
- Feb 2025Shortage declared over. The FDA says the semaglutide shortage is resolved. That starts the clock on compounding limits.
- Apr to May 2025Compounding winds down. 503A pharmacy compounding restrictions take effect in April, 503B in May. The cheap compounded supply starts to narrow.
- Feb 2026A brief price floor. One program lists a $99 oral compounded pill. It is withdrawn within days under manufacturer legal pressure. It was never a stable market price.
- Jun 2026Where it landed. Surviving compounded programs settle around $178 to $209 a month, while branded Wegovy and Zepbound run past $1,000 in cash.
How we rank
Every program earns a 0 to 10 score across five equal-weighted pillars: pricing, cancellation terms, onboarding speed, medication options, and member feedback. The ranking is that score, sorted. We verify prices against each program's published page every Monday. See the full methodology.
Some visit links earn us a commission. Rankings are set from the score before any program is contacted, and a commission never changes a score or a position. Affiliate disclosure.
Frequently asked questions
How are GLP-1 programs scored?
Each program gets a published 1-to-10 GLP Chart score across five dimensions: pricing transparency, cancellation terms, onboarding speed, medication options and member feedback. Scores currently run 5.8 to 8.2. Rankings are the score sorted, re-scored monthly, and a commission never changes a score or a position.
What is the price spread across ranked programs?
Compounded semaglutide starts at about $149 a month at the cheapest cash-pay program and runs to about $299 a month at a maintenance dose. The cheapest program that holds one flat price at every dose with no lock-in is Mochi Health at $178 a month. The highest headline price on the chart is $448 a month at LifeMD. Every headline is a program's cheapest all-in route, so a dearer drug at the same program can cost more. Prices are verified against each program's published pricing every Monday.
How often does the ranking change?
The full re-score runs monthly; the current edition is the June 2026 ranking. Prices are checked every Monday in between, and a price change large enough to move a score is applied at the next monthly re-score with the change noted on the program page.
For picks by situation rather than by score, see best GLP-1 programs by use case.
