GLP-1 clinical trials enrolling now, US

55 clinical trials enrolling across 33 conditions, 26 sponsors, and 46states. Find a clinical trial that's enrolling near you. Synced quarterly from ClinicalTrials.gov.

55 clinical trials33 conditions26 sponsors46 US statesLast synced 2026-05-28
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55 of 55 clinical trials match
  • Who can join
    Adults 18+, have fatty liver disease (also called MASH or NASH), BMI 25+.
    What you take
    retatrutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 6.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)Study ID: NCT07165028Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: retatrutideSites: 140 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 8 to 18, are overweight.
    What you take
    cagrilintide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 7.7 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightStudy ID: NCT07253285Phase: Phase 3Sponsor: Novo Nordisk A/SStudy drug: cagrilintideSites: 34 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity who also have ongoing low back pain, BMI 27+.
    What you take
    retatrutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.3 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back PainStudy ID: NCT07035093Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: retatrutideSites: 25 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have fatty liver disease (also called MASH or NASH), BMI 25+.
    What you take
    survodutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: LIVERAGE - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisStudy ID: NCT06632457Phase: Phase 3Sponsor: Boehringer IngelheimStudy drug: survodutideSites: 124 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have fatty liver disease (also called MASH or NASH) with liver scarring (fibrosis).
    What you take
    survodutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 7.3 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: LIVERAGE: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver FibrosiStudy ID: NCT06632444Phase: Phase 3Sponsor: Boehringer IngelheimStudy drug: survodutideSites: 165 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have high blood pressure.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.4 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1Study ID: NCT06948435Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 28 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, are overweight, BMI 27+.
    What you take
    cagrisema, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightStudy ID: NCT07357766Phase: Phase 3Sponsor: Novo Nordisk A/SStudy drug: cagrisemaSites: 26 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity, BMI 35+.
    What you take
    cagrisema, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.9 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or WithoutStudy ID: NCT07564414Phase: Phase 3Sponsor: Novo Nordisk A/SStudy drug: cagrisemaSites: 99 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have osteoarthritis (joint pain), BMI 27+.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.7 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeStudy ID: NCT07153471Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 26 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have peripheral artery disease (poor blood flow in the legs), BMI 23+.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.7 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Efficacy and Safety of Orforglipron in Participants With Peripheral Artery DiseaseStudy ID: NCT07223593Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 30 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have high blood pressure.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.4 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2Study ID: NCT06952530Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 28 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have high blood pressure, BMI 25+.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.4 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)Study ID: NCT06948422Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 29 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 10 to 18, have type 2 diabetes.
    What you take
    cagrisema, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 3.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiStudy ID: NCT07282613Phase: Phase 3Sponsor: Novo Nordisk A/SStudy drug: cagrisemaSites: 21 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity, BMI 27+.
    What you take
    retatrutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or OverweightStudy ID: NCT07357415Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: retatrutideSites: 20 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, women only, have stress urinary incontinence (bladder leaks), BMI 27+.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.5 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or OverweightStudy ID: NCT07202884Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 21 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have alcohol-related liver disease, BMI 25+.
    What you take
    pemvidutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.2 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)Study ID: NCT07009860Phase: Phase 2Sponsor: Altimmune, Inc.Study drug: pemvidutideSites: 42 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 70, have ulcerative colitis, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and ObeStudy ID: NCT06937086Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 37 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity, BMI 35+.
    What you take
    KAI-9531, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.3 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do NoStudy ID: NCT07284979Phase: Phase 3Sponsor: KaileraStudy drug: KAI-9531Sites: 25 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 70, have Crohn's disease, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.9 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightStudy ID: NCT06937099Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 35 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 6 to 17, have obesity.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.3 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)Study ID: NCT06672549Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 16 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 64, have type 2 diabetes, BMI 25+.
    What you take
    cagrisema, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 14 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesStudy ID: NCT07357740Phase: Phase 2Sponsor: Novo Nordisk A/SStudy drug: cagrisemaSites: 21 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 12 to 17, have obesity.
    What you take
    orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 6.2 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related ComorbiditiesStudy ID: NCT06672939Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: orforglipronSites: 14 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have obesity, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.3 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightStudy ID: NCT06143956Phase: Phase 2Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 49 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have type 2 diabetes, BMI 27+.
    What you take
    LY3457263, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideStudy ID: NCT06897475Phase: Phase 2Sponsor: Eli Lilly and CompanyStudy drug: LY3457263Sites: 25 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have psoriasis, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 3.2 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With ModeStudy ID: NCT06857942Phase: Phase 4Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 40 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have psoriatic arthritis, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.7 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and OStudy ID: NCT06864026Phase: Phase 4Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 53 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have type 2 diabetes.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 18 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesStudy ID: NCT07415954Phase: Phase 2Sponsor: Novo Nordisk A/SStudy drug: semaglutideSites: 23 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 12 to 17, have obesity.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 6.5 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)Study ID: NCT06439277Phase: Phase 3Sponsor: Eli Lilly and CompanyStudy drug: tirzepatideSites: 15 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have obesity or are overweight, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 16 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight ParticipantsStudy ID: NCT06737042Phase: Phase 2Sponsor: Gan and Lee Pharmaceuticals, USAStudy drug: tirzepatideSites: 20 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have chronic kidney disease, BMI 27+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic KidnStudy ID: NCT06717698Phase: Phase 2Sponsor: Novo Nordisk A/SStudy drug: semaglutideSites: 18 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 80, have obesity, BMI 27+.
    What you take
    ecnoglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 7 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-RelatStudy ID: NCT07553299Phase: Phase 2Sponsor: Verdiva Bio Dev LimitedStudy drug: ecnoglutideSites: 17 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 70, have type 2 diabetes, BMI 25+.
    What you take
    icovamenib 100 mg, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 15 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based TheStudy ID: NCT07502508Phase: Phase 2Sponsor: Biomea Fusion Inc.Study drug: icovamenib 100 mgSites: 16 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 40 to 80, have type 2 diabetes.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 6.5 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 DiabetesStudy ID: NCT05390892Phase: Phase 4Sponsor: Brigham and Women's HospitalStudy drug: semaglutideSites: 36 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 65, have nausea and vomiting, BMI 25+.
    What you take
    Tradipitant, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 9 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist UseStudy ID: NCT07446439Phase: Phase 3Sponsor: Vanda PharmaceuticalsStudy drug: TradipitantSites: 10 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have obesity, BMI 30+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 8 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) TrialStudy ID: NCT07505303Phase: Phase 2Sponsor: EccogeneStudy drug: semaglutideSites: 15 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.7 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Study ID: NCT07400107Phase: Phase 3Sponsor: Novo Nordisk A/SStudy drug: semaglutideSites: 10 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 65 to 100, have obesity or are overweight, BMI 35+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor AgonistStudy ID: NCT07446998Phase: Phase 2Sponsor: Veru Inc.Study drug: semaglutideSites: 10 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 19 to 80, have obesity or are overweight, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 16 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or ObeseStudy ID: NCT06732245Phase: Phase 2Sponsor: Biomed Industries, Inc.Study drug: tirzepatideSites: 8 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have obesity, BMI 30+.
    What you take
    cagrilintide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 18 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsStudy ID: NCT07607587Phase: Phase 1Sponsor: Novo Nordisk A/SStudy drug: cagrilintideSites: 11 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 65, have obesity, BMI 30+.
    What you take
    cagrisema, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.1 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietStudy ID: NCT07184086Phase: Phase 1Sponsor: Novo Nordisk A/SStudy drug: cagrisemaSites: 2 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 65, have obesity or are overweight, BMI 27+.
    What you take
    olatorepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 9 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the USStudy ID: NCT07431086Phase: Phase 2Sponsor: Regeneron PharmaceuticalsStudy drug: olatorepatideSites: 3 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 40 to 80, have knee osteoarthritis (joint pain), BMI 18.5+.
    What you take
    liraglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 15 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and OsteoarthritisStudy ID: NCT07225829Phase: Phase 2Sponsor: 4Moving BiotechStudy drug: liraglutideSites: 3 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have type 2 diabetes.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesStudy ID: NCT06246799Phase: Phase 3Sponsor: The University of Texas Health Science Center at San AntonioStudy drug: tirzepatideSites: 2 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have opioid use disorder, BMI 23+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use DisorderStudy ID: NCT06651177Phase: Phase 2Sponsor: T. John Winhusen, PhDStudy drug: tirzepatideSites: 9 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have obesity or are overweight, BMI 30+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 3.2 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial FibrillationStudy ID: NCT06499857Phase: Phase 3Sponsor: University of ChicagoStudy drug: semaglutideSites: 2 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 49, have type 1 diabetes, BMI 20+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.5 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Type 1 Diabetes Impacts of Semaglutide on Cardiovascular OutcomesStudy ID: NCT05819138Phase: Phase 3Sponsor: University of Colorado, DenverStudy drug: semaglutideSites: 2 US
    View on ClinicalTrials.gov →
  • Who can join
    Ages 12 to 35, women only, have polycystic ovary syndrome (PCOS), BMI 27+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary SyndromeStudy ID: NCT05819853Phase: Phase 3Sponsor: University of Colorado, DenverStudy drug: semaglutideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Ages 12 to 45, have obesity, BMI 35+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 4.9 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Brain Plasticity and GLP-1 Receptor Agonist Treatment for ObesityStudy ID: NCT07021937Phase: Phase 3Sponsor: University of Colorado, DenverStudy drug: semaglutideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 80, have alcohol use disorder, BMI 21+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the EffiStudy ID: NCT07218354Phase: Phase 3Sponsor: VA Office of Research and DevelopmentStudy drug: semaglutideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 65+, women only, have type 2 diabetes, BMI 27+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.6 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With DiabetesStudy ID: NCT07428746Phase: Phase 3Sponsor: Emory UniversityStudy drug: semaglutideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 30 to 65, have obesity or are overweight, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 10 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)Study ID: NCT07298915Phase: Phase 3Sponsor: University of VirginiaStudy drug: tirzepatideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Children and teens 12 to 18, have obesity, BMI 35+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 7.4 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Early Re-Initiation of Semaglutide Post Sleeve Gastrectomy in YouthStudy ID: NCT06934655Phase: Phase 3Sponsor: Children's Hospital Los AngelesStudy drug: semaglutideSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18+, have hormone-receptor-positive breast cancer, BMI 27+.
    What you take
    tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 2.9 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast CancerStudy ID: NCT06518837Phase: Phase 2Sponsor: Rutgers, The State University of New JerseyStudy drug: tirzepatideSites: 7 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 40 to 85, are joining a healthy-aging study, BMI 22+.
    What you take
    Metformin, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The study runs about 8 months.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-CessationStudy ID: NCT07092618Phase: Phase 2Sponsor: AgelessRxStudy drug: MetforminSites: 1 US
    View on ClinicalTrials.gov →
  • Who can join
    Adults 18 to 75, have opioid use disorder, BMI 18+.
    What you take
    semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
    How long
    The full study runs about 1.8 years; your own time in it is usually shorter.
    What you get
    The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
    Study details
    Full title: GLP-1R Agonist Treatment for Opioid Use DisorderStudy ID: NCT06548490Phase: Phase 2Sponsor: Milton S. Hershey Medical CenterStudy drug: semaglutideSites: 3 US
    View on ClinicalTrials.gov →

How this directory works

The data comes from ClinicalTrials.gov, the US federal registry for clinical research. We pull active and pre-active GLP-1 trials (semaglutide, tirzepatide, liraglutide, retatrutide, survodutide, orforglipron, cagrisema and related molecules) plus studies of GLP-1 effects on conditions like obesity, type 2 diabetes, MASH, sleep apnea, CKD, and cardiovascular disease.

We sync the data quarterly. To verify a trial is still recruiting before you contact a site, click the ClinicalTrials.gov link on the trial page. That registry is the official source of truth.

How to enroll in a clinical trial

  1. Find a clinical trial below or take the matching quiz. Read the eligibility criteria. The key inclusion and exclusion items are the ones the trial coordinator will check first.
  2. Find a site location near you. We list every US site with city, state, and contact information when the sponsor publishes it.
  3. Contact the site directly using the phone or email on the trial page. Tell them you read about the trial on GLP Chart and you want to be screened.
  4. Screening typically involves a phone call, a clinic visit, and sometimes blood work. Most trials cover the cost of screening and trial-related medical care. Some sites compensate participants for their time; the trial coordinator explains what each site offers.
  5. If you do not qualify for the trial you contacted, ask the site coordinator about other trials they run. Many sites run multiple GLP-1 studies at once and can route you to a better fit.

GLP Chart is not affiliated with any of the sponsors or sites listed. We do not enroll patients in trials. We do not receive payment for any individual enrollment as of the date of this directory. Future commercial relationships with clinical research organizations may exist; if so they will be disclosed here and in the affiliate disclosure.

Participating in a clinical trial is a serious medical decision. Talk to your existing healthcare provider before enrolling. Trial coordinators are required by federal regulation to walk you through informed consent before you join.

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. No removal of unfavorable information at advertiser request. Pricing is pulled from each program's public-facing page weekly.