A study testing whether a new weekly shot, tirzepatide, can help people drink less.
Recruiting now. Registry record last updated July 9, 2026.
- Who can join
- Adults 18+, have alcohol use disorder, BMI 23+.
- What you take
- tirzepatide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
- How long it lasts
- The full study runs about 1.8 years; your own time in it is usually shorter.
- What you get
- Many clinical trials pay for the study medication and the study visits. Some also pay for travel. Ask the study team what this one covers before you sign the consent form.
What this study is for
Primary condition: Alcohol Use Disorder (AUD).
Full scientific study title: Study of Tirzepatide for Recovery and Alcohol Use Management.
Who can join
Adults 18+, have alcohol use disorder, BMI 23+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- English speaking adults aged 18 and above
- Diagnosed with current DSM-5 alcohol use disorder
- Willing and able to physically travel to BWH CCI outpatient facilities for study visits
Key exclusion criteria
- CIWA score at screening ≥ 8.
- Psychotic disorder, active suicidality or homicidality or any psychiatric condition that impair ability to provide informed consent
- Any lifetime diagnosis of eating disorders including anorexia, bulimia, binge eating, or avoidant/restrictive food intake disorder
- BMI\<23 mg/kg2
- Current or lifetime diagnosis of Type 1 or Type 2 diabetes
Where this trial is enrolling
This trial has 2 sites across 1 state. Contact a site coordinator directly to start screening.
Massachusetts2 sites
- Brigham and Women's HospitalBoston, Massachusetts
- Brigham and Women's Faulkner HospitalJamaica Plain, Massachusetts
Timeline
Started enrolling: September 15, 2025. Expected completion: July 1, 2027. Last updated on ClinicalTrials.gov: July 9, 2026.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked August 21, 2026. Confirm the current status there before you contact a site:
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