A study testing whether a GLP-1 medicine from Gila Therapeutics, semaglutide, can help people lose weight.
Recruiting now. Registry record last updated July 27, 2026.
- Who can join
- Adults 18 to 65, have obesity or are overweight, BMI 30+.
- What you take
- semaglutide, given as part of the study. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The study runs about 11 months.
- What you get
- Many clinical trials pay for the study medication and the study visits. Some also pay for travel. Ask the study team what this one covers before you sign the consent form.
What this study is for
Primary condition: Obesity & Overweight.
Full scientific study title: A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity.
Who can join
Adults 18 to 65, have obesity or are overweight, BMI 30+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Body Mass Index 30 to 45
Key exclusion criteria
- Type 2 Diabetes Mellitus
- Multiple Endocrine Neoplasia Type 2
- Medullary thyroid cancer
Where this trial is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Minnesota1 site
- Clinical Research Institute of MinnesotaMinneapolis, Minnesota
Timeline
Started enrolling: June 17, 2026. Expected completion: May 2027. Last updated on ClinicalTrials.gov: July 27, 2026.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked August 10, 2026. Confirm the current status there before you contact a site:
Other GLP-1 clinical trials
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