A study testing whether a GLP-1 medicine from Novo Nordisk, semaglutide, can help with weight.

Who can join
Adults 18+, have obesity.
What you take
semaglutide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
How long it lasts
The study runs about 8 months.
What you get
The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
Phase Phase 1Sponsor Novo Nordisk A/SDrug semaglutideClass GLP-1 RASites 1 USEnrollment target 75

What this study is for

Primary condition: Obesity.

Full scientific study title: Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in Peop.

Who can join

Age18 and upSexAny

Adults 18+, have obesity. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key exclusion criteria

  • Previous dosing in this study.
  • Previous rescreening for this study.
  • Female who is pregnant, breast-feeding or intends to become pregnant or is of childbearing potential and not using adequate contraceptive method
  • Current participation (i.e., signed informed consent) in any other interventional clinical study.
  • Exposure to investigational medicinal products, except maintenance treatment with liraglutide 3.0 mg, oral semaglutide 25 mg, or semaglutide 2.4 mg as required by the inclusion criterion, within 30 days or 5 half-lives of the investigational medicinal product (if known), which-ever is longer, before screening (Visit 1).

Where this study is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

California1 site
  • Altasciences Clinical LA, Inc.
    Cypress, California

Timeline

Started enrolling: 2025-11-07. Expected completion: 2026-07-17. Last updated on ClinicalTrials.gov: 2026-06-16.

Official source

We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:

View on ClinicalTrials.gov →

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