Enrolling now · NCT07092618

A study testing whether metformin from AgelessRx, a long-used diabetes pill, affects healthy aging.

Who can join
Adults 40 to 85, are joining a healthy-aging study, BMI 22+.
What you take
Metformin, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
How long it lasts
The study runs about 8 months.
What you get
The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
Phase Phase 2Sponsor AgelessRxDrug MetforminClass OtherSites 1 USEnrollment target 150

What this study is for

Full study title: Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation.

Primary condition: Longevity. Also studied in: GLP-1, Geroscience, Aging.

Who can join, in detail

Age 40 to 85
Sex All
BMI 22+

Key inclusion criteria

  • Existing AgelessRx patient
  • Adults (40 - 85 years of age)
  • Any sex
  • Any ethnicity
  • BMI >= 22 kg/m^2

Key exclusion criteria

  • Individuals who are denied a longevity product by the AgelessRx medical team will not be asked to participate in any product specific test(s) or questionnaire(s)
  • History of bariatric surgery
  • Use of weight-loss medications other than GLP-1s within the past 6 months
  • Age <40 years
  • Contraindications to naltrexone, metformin, or rapamycin

Where this study is enrolling

This trial has 1 US sites across 1 states. Contact the site coordinator directly to start the screening process.

Illinois

Timeline

Started enrolling: 2024-12-17. Expected completion: 2025-08. Last updated on ClinicalTrials.gov: 2025-07-30.

Official source

We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:

View on ClinicalTrials.gov →

Back to the full directory → or take the matching quiz if you want clinical trials filtered to your conditions and location.

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. No removal of unfavorable information at advertiser request. Pricing is pulled from each program's public-facing page weekly.