A study testing whether an investigational medicine from Novo Nordisk, NNC0662-0419, can help people lower blood sugar.

Recruiting now. Registry record last updated August 10, 2026.

Who can join
Adults 18 to 75, have type 2 diabetes.
What you take
NNC0662-0419, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
How long it lasts
The study runs about 18 months.
What you get
Many clinical trials pay for the study medication and the study visits. Some also pay for travel. Ask the study team what this one covers before you sign the consent form.
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Phase Phase 2Sponsor Novo Nordisk A/SDrug NNC0662-0419Class OtherSites 23 USEnrollment target 270

What this study is for

Primary condition: Diabetes Mellitus, Type 2.

Full scientific study title: A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes.

Who can join

Age18 to 75SexAny

Adults 18 to 75, have type 2 diabetes. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Male or female (sex at birth).
  • Age 18-75 years (both inclusive) at the time of signing the informed consent.
  • Glycated haemoglobin (HbA1c) of 7.0-10.0 percent (%) (53-86 millimoles per mole \[mmol/mol\]) (both inclusive) as assessed by central laboratory at screening.
  • Willingness to obtain a high weight loss (greater than \[\>\] 25% of weight at baseline).

Key exclusion criteria

  • Treatment with any medication for the indication of diabetes or obesity other than stated in the inclusion criteria within 90 days before screening. However, short term insulin treatment for a maximum of 14 consecutive days and prior insulin treatment for gestational diabetes are allowed.
  • Uncontrolled and potentially unstable diabetic retinopathy or maculopathy. Pharmacological pupil-dilation is a requirement unless using a digital fundus photography camera specified for non-dilated examination.
  • Known hypoglycaemic unawareness as indicated by the investigator according to Clarke's Questionnaire.

Where this trial is enrolling

This trial has 23 sites across 11 states. Contact a site coordinator directly to start screening.

California6 sites
  • First Valley Medical Group
    Lancaster, California
  • Torrance Clinical Research Institute, Inc.
    Lomita, California
  • Ark Clinical Research
    Long Beach, California
  • Pacific Clinical Studies
    Los Alamitos, California
  • Wetlin Research Associates, Inc.
    San Diego, California
  • Diablo Clinical Research, Inc.
    Walnut Creek, California
Florida5 sites
  • Encore Medical Research LLC
    Hollywood, Florida
  • Bioclinical Research Alliance
    Miami, Florida
  • South Broward Research LLC
    Miramar, Florida
  • West Orange Endocrinology
    Ocoee, Florida
  • Encore Medical Research of Weston
    Weston, Florida
Idaho1 site
  • Elite Clinical Trials
    Blackfoot, Idaho
Illinois1 site
  • Cedar-Crosse Research Center
    Chicago, Illinois
Massachusetts1 site
  • Brigham & Women's Hospital
    Boston, Massachusetts
Missouri1 site
  • Headlands Research
    Springfield, Missouri
North Carolina2 sites
  • PharmQuest
    Greensboro, North Carolina
  • Piedmont Healthcare Statesville
    Statesville, North Carolina
Ohio1 site
  • Providence Center for Clinical Research
    Dayton, Ohio
Tennessee1 site
  • CNS Healthcare
    Memphis, Tennessee
Texas3 sites
  • University of Texas Southwestern Medical Center
    Dallas, Texas
  • JCCT- Juno NW Houston
    Houston, Texas
  • Consano Clinical Research, LLC
    Shavano Park, Texas
West Virginia1 site
  • Frontier Clinical Research - Kingwood
    Kingwood, West Virginia

Timeline

Started enrolling: April 17, 2026. Expected completion: October 1, 2027. Last updated on ClinicalTrials.gov: August 10, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked August 21, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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