A study testing whether a new weekly shot, tirzepatide, can help people with binge eating disorder lose weight.

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

• Have a BMI ≥30 kg/m2 or ≥27 kg/m2
• previously diagnosed with at least one obesity-related comorbidity:
• Have at least one self-reported unsuccessful dietary effort to lose body weight
• Meet Diagnostic and Statistical Manual (DSM)-5 criteria for Binge Eating Disorder (BED) as diagnosed by the Eating Disorder Examination interview and confirmed by binge-eating diaries that is moderate or greater in severity (4 or more episodes per week)
• Are 18 years of age or older

Key exclusion criteria

• Current diagnosis of bulimia nervosa or anorexia nervosa
• Have type 1 diabetes mellitus (T1DM) or Type 2 diabetes mellitus (T2DM), history of ketoacidosis, or hyperosmolar state/coma
• Have laboratory evidence diagnostic of diabetes mellitus during screening, including an HbA1c ≥6.5% or fasting glucose \>126 mg/dL
• Have a self-reported change in body weight \>5 kg within 3 months prior to screening
• Have a prior or planned surgical treatment for obesity (excluding lap-band if removed \>6 months prior to screening or liposuction or abdominoplasty if performed \>1 year prior to screening)