GLP-1 clinical trials in Illinois: 30 recruiting now
42 sites in 11 Illinois cities. Registry checked October 16, 2026.
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Weight-loss studies (10)
Weight-loss study of cagrisema
Where: Chicago, Gillespie, Gurnee and 1 more city
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 35+.
Study record on ClinicalTrials.gov
Cedar-Crosse Research Center, Chicago
Macoupin Fam Practice Ctr, LLP, Gillespie
Clinical Investigation Spec Gurnee, Gurnee
Endeavor Health, Skokie
Evanston Premier Hlthcr Res, Skokie
Weight-loss study of orforglipron
Where: Chicago
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 6 to 17 with obesity.
Call the site: 312-503-1499Study record on ClinicalTrials.gov
Ann and Robert Lurie Children's Hospital of Chicago, Chicago. 312-503-1499
University of Illinois at Chicago, Chicago. 773-702-2879
Weight-loss study of maridebart cafraglutide
Where: Skokie and Springfield
What: Tests whether a study medicine from Amgen, Maridebart Cafraglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity or overweight, BMI 25+.
Study record on ClinicalTrials.gov
Endeavor Health, Skokie
Central Illinois Diabetes and Clinical Research, a Division of Prairie Education and Research Cooper, Springfield
Show 7 more studies
Weight-loss study of semaglutide
Where: Chicago and Skokie
What: Tests whether a GLP-1 medicine from Novo Nordisk, semaglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight.
Study record on ClinicalTrials.gov
Chicago Research Center, Inc, Chicago
Endeavor Health, Skokie
Weight-loss study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people lose weight.
Free to join
Who can join: Children and teens 6 to 11 with obesity.
Call the site: 630-642-9702. 312-227-3604Study record on ClinicalTrials.gov
Ann and Robert H Lurie Children's Hospital of Chicago, Chicago. 630-642-9702. 312-227-3604
University of Illinois at Chicago, Chicago. 773-702-2879
Weight-loss study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people lose weight.
Free to join
Who can join: Children and teens 12 to 17 with obesity.
Study record on ClinicalTrials.gov
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Weight-loss study of orforglipron
Where: Chicago
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 12 to 17 with obesity.
Study record on ClinicalTrials.gov
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Weight-loss study of cagrilintide
Where: Oak Park
What: Tests whether a study medicine from Novo Nordisk, cagrilintide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 27+.
Study record on ClinicalTrials.gov
Walgreens - Store 11760, Oak Park
Weight-loss study of olatorepatide
Where: Chicago and Oak Brook
What: Tests whether a GLP-1 and GIP medicine from Regeneron Pharmaceuticals, olatorepatide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity or overweight, BMI 27+.
Study record on ClinicalTrials.gov
Charter Research LLC - Chicago, Chicago
Flourish Research - Chicago, Chicago
AMR Clinical - Chicago Oak Brook, Oak Brook
Weight-loss study of LY3305677
Where: Chicago and Skokie
What: Tests whether an investigational medicine from Lilly, LY3305677, can help people lose weight.
Free to join
Who can join: Adults 18 to 75 with obesity, BMI 27+.
Study record on ClinicalTrials.gov
Great Lakes Clinical Trials - Ravenswood, Chicago
NorthShore University Health System, Skokie
Type 2 diabetes studies (5)
Type 2 diabetes study of cagrisema
Where: Springfield
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Children and teens 10 to 18 with type 2 diabetes.
Study record on ClinicalTrials.gov
SIU Medicine, Springfield
Type 2 diabetes study of semaglutide
Where: Melrose Park
What: Tests whether a GLP-1 medicine, semaglutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Study record on ClinicalTrials.gov
Research Site, Melrose Park
Type 2 diabetes study of survodutide
Where: Skokie
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Evanston Premier Healthcare Research LLC, Skokie. 833-602-2368
Show 2 more studies
Type 2 diabetes study of cagrisema
Where: Skokie
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 25+.
Study record on ClinicalTrials.gov
Endeavor Health, Skokie
Type 2 diabetes study of NNC0662-0419
Where: Chicago
What: Tests whether an investigational medicine from Novo Nordisk, NNC0662-0419, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes.
Study record on ClinicalTrials.gov
Cedar-Crosse Research Center, Chicago
Other GLP-1 studies in Illinois (15)
Atrial fibrillation study of semaglutide
Where: Chicago
What: Tests whether a GLP-1 medicine, semaglutide, can help people with atrial fibrillation lose weight.
Free to join
Who can join: Adults 18 to 75 with obesity or overweight, BMI 30+.
Call the site: 773-702-3275Study record on ClinicalTrials.gov
University of Chicago, Chicago. 773-702-3275
Ulcerative colitis study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with ulcerative colitis calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with ulcerative colitis, BMI 27+.
Study record on ClinicalTrials.gov
Rush University Medical Center, Chicago
Crohn's disease study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with Crohn's disease calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with Crohn's disease, BMI 27+.
Study record on ClinicalTrials.gov
Rush University Medical Center, Chicago
Show 12 more studies
Fatty liver disease (MASLD) study of retatrutide
Where: Chicago
What: Tests whether a GLP-1, GIP and glucagon medicine from Lilly, retatrutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (MASLD), BMI 25+.
Study record on ClinicalTrials.gov
University of Chicago Medical Center, Chicago
Alcohol use disorder study of semaglutide
Where: Hines
What: Tests whether a GLP-1 medicine, semaglutide, can help people with alcohol use disorder drink less.
Free to join
Who can join: Adults 18 to 80 with alcohol use disorder, BMI 21+.
Call the site: 708-202-8387Study record on ClinicalTrials.gov
Edward Hines Jr. VA Hospital, Hines, IL, Hines. 708-202-8387
Prehypertension study of orforglipron
Where: Chicago
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people with prediabetes lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 25+.
Call the site: 773-275-3500 Ext 162Study record on ClinicalTrials.gov
Great Lakes Clinical Trials - Ravenswood, Chicago. 773-275-3500 Ext 162
ASCVD study of semaglutide
Where: Chicago and Hinsdale
What: Tests whether a GLP-1 medicine, semaglutide, can help people lower blood sugar.
Free to join
Who can join: Adults 40 to 80 with type 2 diabetes.
Call the site: 773-505-0169Study record on ClinicalTrials.gov
University of Illinois Chicago, Chicago. 773-505-0169
Rush University Medical Center, Hinsdale. 630-724-1792
Opioid use disorder study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine, tirzepatide, can help people with opioid use disorder cut down on opioids.
Free to join
Who can join: Adults 18+ with opioid use disorder, BMI 23+.
Call the site: 312-572-4753Study record on ClinicalTrials.gov
Ruth M. Rothstein CORE Center, Chicago. 312-572-4753
Chronic kidney disease study of NNC0519-0130
Where: Skokie
What: Tests whether an investigational medicine from Novo Nordisk, NNC0519-0130, can help people with chronic kidney disease protect their kidneys.
Free to join
Who can join: Adults 18+ with chronic kidney disease, BMI 27+.
Study record on ClinicalTrials.gov
Endeavor Health, Skokie
Longevity study of metformin
Where: Chicago
What: Tests whether a long-used diabetes pill, metformin, affects healthy aging.
Free to join
Who can join: Adults 40 to 85 who are joining a healthy-aging study, BMI 22+.
Call the site: 650-272-3169Study record on ClinicalTrials.gov
AgelessRx, Chicago. 650-272-3169
Smoking cessation study of tirzepatide
Where: Chicago
What: Tests whether a GLP-1 and GIP medicine, tirzepatide, can help people quit smoking.
Free to join
Who can join: Adults 21 to 65 who are trying to quit smoking, BMI 25+.
Call the site: 773-834-2244Study record on ClinicalTrials.gov
University of Chicago Pritzker School of Medicine, Chicago. 773-834-2244
Abdominal wall hernia study of semaglutide
Where: Chicago
What: Tests a GLP-1 medicine, semaglutide, in people with abdominal wall hernia.
Free to join
Who can join: Adults 18+ with abdominal wall hernia, BMI 40+.
Call the site: 312-907-1414Study record on ClinicalTrials.gov
Northwestern University, Chicago. 312-907-1414
Blood glucose study
Where: Addison
Free to join
Who can join: Adults 18 to 45, BMI 18.5+.
Call the site: 630-330-0463Study record on ClinicalTrials.gov
Biofortis Innovation Services, Addison. 630-330-0463
Multiple sclerosis study
Where: Chicago
What: A study in people with multiple sclerosis.
Free to join
Who can join: Adults 18 to 70 with multiple sclerosis, BMI 24+.
Call the site: 240-362-4800Study record on ClinicalTrials.gov
Northwestern Memorial Hospital, Chicago. 240-362-4800
Prediabetes study
Where: Addison
What: A study in people with prediabetes.
Free to join
Who can join: Adults 35 to 65 with prediabetes, BMI 25+.
Call the site: (630) 617-2000Study record on ClinicalTrials.gov
Merieux NutriSciences, Addison. (630) 617-2000
Source: ClinicalTrials.gov, the federal registry, read October 16, 2026. Open a study's registry record before you call: it can close to new participants at any time. GLP Chart does not enroll anyone, is not paid for clinical-trial referrals and has no relationship with any sponsor or site on this page.
Clinical trials by state
Every state with a GLP-1 study recruiting today. 48 of them.
- Alabama (18)
- Arizona (22)
- Arkansas (5)
- California (53)
- Colorado (18)
- Connecticut (14)
- Delaware (1)
- District of Columbia (1)
- Florida (43)
- Georgia (23)
- Hawaii (6)
- Idaho (12)
- Illinois (30)
- Indiana (20)
- Iowa (10)
- Kansas (14)
- Kentucky (18)
- Louisiana (14)
- Maine (1)
- Maryland (25)
- Massachusetts (20)
- Michigan (21)
- Minnesota (19)
- Mississippi (7)
- Missouri (22)
- Montana (3)
- Nebraska (7)
- Nevada (11)
- New Hampshire (3)
- New Jersey (11)
- New Mexico (5)
- New York (30)
- North Carolina (31)
- North Dakota (5)
- Ohio (31)
- Oklahoma (12)
- Oregon (5)
- Pennsylvania (33)
- Rhode Island (5)
- South Carolina (25)
- South Dakota (2)
- Tennessee (27)
- Texas (56)
- Utah (14)
- Virginia (28)
- Washington (24)
- West Virginia (5)
- Wisconsin (7)