GLP-1 clinical trials in North Carolina: 30 recruiting now
71 sites in 18 North Carolina cities. Registry checked October 2, 2026.
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Weight-loss studies (10)
Weight-loss study of cagrisema
Where: Greensboro, Greenville, Morehead City and 2 more cities
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 35+.
Study record on ClinicalTrials.gov
PharmQuest Life Sciences LLC, Greensboro
Physician's East Endocrinology, Greenville
Carteret Medical Group, Morehead City
Centricity Rsrch MHCity Multi, Morehead City
Piedmont Healthcare/Research, Statesville
and 1 more site
Accellacare Wilmington, Wilmington
Weight-loss study of orforglipron
Where: Chapel Hill, Durham and Morehead City
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 6 to 17 with obesity.
Call the site: 252-222-5700 ext. 195Study record on ClinicalTrials.gov
UNC Children's Hospital, Chapel Hill
Duke Children's Primary Care, Durham
Lucas Research, Inc, Morehead City. 252-222-5700 ext. 195
Weight-loss study of maridebart cafraglutide
Where: Morehead City, Raleigh and Wilmington
What: Tests whether a study medicine from Amgen, Maridebart Cafraglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity or overweight, BMI 25+.
Study record on ClinicalTrials.gov
Centricity Research Morehead City Specialty, Morehead City
Accellacare of Raleigh, Raleigh
Accellacare Research of Wilmington, Wilmington
Show 7 more studies
Weight-loss study of KAI-9531
Where: Morehead City and Morrisville
What: Tests whether an investigational medicine from Kailera, KAI-9531, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 35+.
Study record on ClinicalTrials.gov
Kailera Clinical Site, Morehead City
Kailera Clinical Site, Morrisville
Weight-loss study of semaglutide
Where: Greensboro and Statesville
What: Tests whether a GLP-1 medicine from Novo Nordisk, semaglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight.
Study record on ClinicalTrials.gov
PharmQuest Life Sciences LLC, Greensboro
Piedmont Healthcare/Research, Statesville
Weight-loss study of cagrilintide
Where: Greensboro and Wilmington
What: Tests whether a study medicine from Novo Nordisk, cagrilintide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 27+.
Study record on ClinicalTrials.gov
PharmQuest, Greensboro
KDCILM, LLC & Accellacare US, Inc., Wilmington
Weight-loss study of orforglipron
Where: Morehead City
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 12 to 17 with obesity.
Study record on ClinicalTrials.gov
Lucas Research, Inc., Morehead City
Weight-loss study of LY3305677
Where: Greensboro, Monroe, Morehead City and 1 more city
What: Tests whether an investigational medicine from Lilly, LY3305677, can help people lose weight.
Free to join
Who can join: Adults 18 to 75 with obesity, BMI 27+.
Call the site: 336-763-6968Study record on ClinicalTrials.gov
Medication Management, Greensboro. 336-763-6968
Monroe Biomedical Research, Monroe. 704-283-7359
Lucas Research, Inc, Morehead City. 252-222-5700
Lucas Research, Inc., New Bern. 252-649-1944
Weight-loss study of cagrilintide
Where: Monroe and Wilmington
What: Tests whether a study medicine from Novo Nordisk, cagrilintide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 30+.
Study record on ClinicalTrials.gov
Monroe Biomedical Research, LLC, Monroe
Accellacare, Wilmington
Weight-loss study
Where: Cary
Free to join
Who can join: Adults 21 to 65 with obesity, BMI 30+.
Call the site: (984) 345-2988Study record on ClinicalTrials.gov
True You Weight Loss, Cary. (984) 345-2988
Type 2 diabetes studies (6)
Type 2 diabetes study of semaglutide
Where: Durham, Morehead City, Raleigh and 2 more cities
What: Tests whether a GLP-1 medicine, semaglutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Study record on ClinicalTrials.gov
Research Site, Durham
Research Site, Morehead City
Research Site, Raleigh
Research Site, Statesville
Research Site, Wilmington
Type 2 diabetes study of survodutide
Where: Fayetteville, Greensboro and Morehead City
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Javara Inc. - Cape Fear Valley Medical Center, Fayetteville. 833-602-2368
PharmQuest Life Sciences, Greensboro. 833-602-2368
Centricity Research - Morehead City, Morehead City. 833-602-2368
Type 2 diabetes study of cagrisema
Where: Greensboro and Wilmington
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 25+.
Study record on ClinicalTrials.gov
PharmQuest Life Sciences LLC, Greensboro
Accellacare Wilmington, Wilmington
Show 3 more studies
Type 2 diabetes study of LY3457263
Where: Morehead City and Shelby
What: Tests whether an investigational medicine from Lilly, LY3457263, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes, BMI 27+.
Call the site: 252-222-5700Study record on ClinicalTrials.gov
Lucas Research, Inc., Morehead City. 252-222-5700
Shelby Clinical Research, Shelby. 9805529230
Type 2 diabetes study of NNC0662-0419
Where: Greensboro and Statesville
What: Tests whether an investigational medicine from Novo Nordisk, NNC0662-0419, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes.
Study record on ClinicalTrials.gov
PharmQuest, Greensboro
Piedmont Healthcare Statesville, Statesville
Type 2 diabetes study of UBT251
Where: Greensboro and Wilmington
What: Tests whether an investigational medicine from Novo Nordisk, UBT251, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes.
Study record on ClinicalTrials.gov
PharmQuest, Greensboro
KDCILM, LLC & Accellacare US, Inc., Wilmington
Other GLP-1 studies in North Carolina (14)
Fatty liver disease with liver scarring study of survodutide
Where: Durham, Fayetteville, Greenville and 2 more cities
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (also called MASH or NASH) with liver scarring (fibrosis).
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Duke University Medical Center, Durham. 833-602-2368
Coastal Research Institute, LLC, Fayetteville. 833-602-2368
Carolina Researche, Greenville. 833-602-2368
Centricity Research (New Bern), New Bern. 833-602-2368
M3 Wake Research, Inc., Raleigh. 833-602-2368
Prehypertension study of orforglipron
Where: Greensboro, Monroe, Morehead City and 1 more city
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people with prediabetes lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 25+.
Call the site: 3367636968Study record on ClinicalTrials.gov
Medication Management, Greensboro. 3367636968
Monroe Biomedical Research, Monroe
West Clinical Research, Morehead City. 2525150050
Trial Management Associates - Wilmington - Floral Parkway, Wilmington
Fatty liver disease (also called MASH or NASH) study of survodutide
Where: Fayetteville, Greenville and Raleigh
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (also called MASH or NASH), BMI 25+.
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Coastal Research Institute, LLC, Fayetteville. 833-602-2368
Carolina Researche, Greenville. 833-602-2368
M3 Wake Research, Inc., Raleigh. 833-602-2368
Show 11 more studies
Fatty liver disease (MASLD) study of retatrutide
Where: Durham, Monroe and Morehead City
What: Tests whether a GLP-1, GIP and glucagon medicine from Lilly, retatrutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (MASLD), BMI 25+.
Call the site: 704-283-7359Study record on ClinicalTrials.gov
Duke University - Main Hospital and Clinics, Durham
Monroe Biomedical Research, Monroe. 704-283-7359
Carteret Medical Group, Morehead City. 252-499-8623
Alcohol use disorder study of semaglutide
Where: Asheville and Durham
What: Tests whether a GLP-1 medicine, semaglutide, can help people with alcohol use disorder drink less.
Free to join
Who can join: Adults 18 to 80 with alcohol use disorder, BMI 21+.
Call the site: 8282987911Study record on ClinicalTrials.gov
Asheville VA Medical Center, Asheville, NC, Asheville. 8282987911
Durham VA Medical Center, Durham, NC, Durham
Ulcerative colitis study of tirzepatide
Where: Fayetteville
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with ulcerative colitis calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with ulcerative colitis, BMI 27+.
Study record on ClinicalTrials.gov
Coastal Research Institute - Fayetteville, Fayetteville
Crohn's disease study of tirzepatide
Where: Fayetteville
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with Crohn's disease calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with Crohn's disease, BMI 27+.
Study record on ClinicalTrials.gov
Coastal Research Institute - Fayetteville, Fayetteville
ASCVD study of semaglutide
Where: Charlotte and Durham
What: Tests whether a GLP-1 medicine, semaglutide, can help people lower blood sugar.
Free to join
Who can join: Adults 40 to 80 with type 2 diabetes.
Call the site: 704-304-7176Study record on ClinicalTrials.gov
Atrium Health Family Medicine Research Department, Charlotte. 704-304-7176
Duke University Hospital, Durham. 919-668-9049
Psoriasis study of tirzepatide
Where: Cary and Huntersville
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people calm psoriasis.
Free to join
Who can join: Adults 18+ with psoriasis, BMI 27+.
Call the site: 800-785-3150Study record on ClinicalTrials.gov
Revival Research Institute, LLC, Cary
Onsite Clinical Solutions - Huntersville, Huntersville. 800-785-3150
Idiopathic intracranial hypertension (IIH) study of tirzepatide
Where: Durham
What: Tests a GLP-1 and GIP medicine, tirzepatide, in people with idiopathic intracranial hypertension (IIH).
Free to join
Who can join: Adults 18 to 60 with idiopathic intracranial hypertension (IIH), BMI 30+.
Call the site: 919-660-1754Study record on ClinicalTrials.gov
Duke University Medical Center, Durham. 919-660-1754
Chronic kidney disease study of NNC0519-0130
Where: Morehead City and Winston-Salem
What: Tests whether an investigational medicine from Novo Nordisk, NNC0519-0130, can help people with chronic kidney disease protect their kidneys.
Free to join
Who can join: Adults 18+ with chronic kidney disease, BMI 27+.
Study record on ClinicalTrials.gov
Carteret Medical Group, Morehead City
Brookview Hills Research Associates, LLC, Winston-Salem
Cardiovascular study of semaglutide
Where: Chapel Hill
What: Tests a GLP-1 medicine, semaglutide, in women going through menopause.
Free to join
Who can join: Adults 45 to 55, women only who are going through menopause.
Call the site: 919-908-0010Study record on ClinicalTrials.gov
University of North Carolina, School of Medicine, Chapel Hill. 919-908-0010
Endometrial cancer study of tirzepatide
Where: Chapel Hill
What: Tests whether a GLP-1 and GIP medicine, tirzepatide, can help people with endometrial cancer lose weight.
Free to join
Who can join: Adults 18+, women only with endometrial cancer, BMI 30+.
Call the site: 919-966-5996Study record on ClinicalTrials.gov
Lineberger Comprehensive Cancer Center, Chapel Hill. 919-966-5996
Diabetes study
Where: Durham
What: A study in people with diabetes.
Free to join
Who can join: Adults 18 to 60 with diabetes.
Call the site: 919-660-6766Study record on ClinicalTrials.gov
Duke Center for Living, Durham. 919-660-6766
Source: ClinicalTrials.gov, the federal registry, read October 2, 2026. Open a study's registry record before you call: it can close to new participants at any time. GLP Chart does not enroll anyone, is not paid for clinical-trial referrals and has no relationship with any sponsor or site on this page.
Clinical trials by state
Every state with a GLP-1 study recruiting today. 48 of them.
- Alabama (17)
- Arizona (22)
- Arkansas (6)
- California (51)
- Colorado (17)
- Connecticut (13)
- Delaware (1)
- District of Columbia (1)
- Florida (42)
- Georgia (23)
- Hawaii (5)
- Idaho (12)
- Illinois (30)
- Indiana (19)
- Iowa (10)
- Kansas (15)
- Kentucky (15)
- Louisiana (15)
- Maine (1)
- Maryland (22)
- Massachusetts (19)
- Michigan (20)
- Minnesota (18)
- Mississippi (6)
- Missouri (21)
- Montana (3)
- Nebraska (5)
- Nevada (13)
- New Hampshire (3)
- New Jersey (12)
- New Mexico (5)
- New York (30)
- North Carolina (30)
- North Dakota (5)
- Ohio (28)
- Oklahoma (12)
- Oregon (5)
- Pennsylvania (33)
- Rhode Island (6)
- South Carolina (24)
- South Dakota (2)
- Tennessee (26)
- Texas (56)
- Utah (14)
- Virginia (28)
- Washington (23)
- West Virginia (5)
- Wisconsin (7)
