GLP-1 clinical trials in Pennsylvania: 33 recruiting now
52 sites in 20 Pennsylvania cities. Registry checked October 16, 2026.
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Weight-loss studies (10)
Weight-loss study of cagrisema
Where: Beaver, Hatboro and Philadelphia
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lose weight.
Free to join
Who can join: Adults 18+ with obesity, BMI 35+.
Study record on ClinicalTrials.gov
Heritage Valley Medical Group, Beaver
Hatboro Med Associates, Hatboro
Northeast Endocrine Metabolic Associates, Philadelphia
Weight-loss study of orforglipron
Where: Pittsburgh
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 6 to 17 with obesity.
Call the site: 412-692-6935Study record on ClinicalTrials.gov
UPMC Children's Hospital of Pittsburgh, Pittsburgh. 412-692-6935
Weight-loss study of orforglipron
Where: Pittsburgh
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people lose weight.
Free to join
Who can join: Children and teens 12 to 17 with obesity.
Study record on ClinicalTrials.gov
Childrens Hospital of Pittsburgh, Pittsburgh
Show 7 more studies
Weight-loss study of cagrilintide
Where: Pittsburgh
What: Tests whether a study medicine from Novo Nordisk, cagrilintide, can help people lose weight.
Free to join
Who can join: Children and teens 8 to 18 who are overweight.
Study record on ClinicalTrials.gov
UPMC Child Hosp-Pittsburgh, Pittsburgh
Weight-loss study of maridebart cafraglutide
Where: Duncansville
What: Tests whether a study medicine from Amgen, Maridebart Cafraglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ with obesity or overweight, BMI 25+.
Study record on ClinicalTrials.gov
Altoona Center for Clinical Research, Duncansville
Weight-loss study of semaglutide
Where: Danville
What: Tests whether a GLP-1 medicine from Novo Nordisk, semaglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight.
Study record on ClinicalTrials.gov
Geisinger Clinic, Danville
Weight-loss study of semaglutide
Where: Philadelphia
What: Tests whether a GLP-1 medicine from Novo Nordisk, semaglutide, can help people lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 27+.
Study record on ClinicalTrials.gov
UPA Ctr Weight and Eating Dis, Philadelphia
Weight-loss study of semaglutide
Where: Lancaster
What: Tests whether a GLP-1 medicine, semaglutide, can help people with type 2 diabetes lose weight.
Free to join
Who can join: Adults 18 to 89 with obesity, BMI 27+.
Call the site: (717)392-4948Study record on ClinicalTrials.gov
Amish Research Clinic, Lancaster. (717)392-4948
Weight-loss study
Where: State College
Free to join
Who can join: Adults 18+, BMI 25+.
Call the site: 425-499-8049Study record on ClinicalTrials.gov
Health, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University, State College. 425-499-8049
Weight-loss study
Where: Pittsburgh
What: A study in adults starting a GLP-1 medicine on their own prescription.
Free to join
Who can join: Adults 18+ with obesity, BMI 27+.
Call the site: 515-817-4601Study record on ClinicalTrials.gov
Physical Activity Research Center, University of Pittsburgh, Pittsburgh. 515-817-4601
Type 2 diabetes studies (5)
Type 2 diabetes study of survodutide
Where: Beaver, Pittsburgh and Uniontown
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Call the site: 833-602-2368Study record on ClinicalTrials.gov
Heritage Valley Medical Group, Beaver. 833-602-2368
Preferred Primary Care Physicians, Pittsburgh. 833-602-2368
Preferred Primary Care Physicians-Pittsburgh-63932, Pittsburgh. 833-602-2368
Preferred Primary Care Physicians - Matthew Drive, Uniontown. 833-602-2368
Type 2 diabetes study of semaglutide
Where: Feasterville-Trevose and Philadelphia
What: Tests whether a GLP-1 medicine, semaglutide, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18+ with type 2 diabetes, BMI 23+.
Study record on ClinicalTrials.gov
Research Site, Feasterville-Trevose
Research Site, Philadelphia
Type 2 diabetes study of cagrisema
Where: Philadelphia
What: Tests whether a study medicine from Novo Nordisk, cagrisema, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Children and teens 10 to 18 with type 2 diabetes.
Study record on ClinicalTrials.gov
Children's Hosptl Philadelphia, Philadelphia
Show 2 more studies
Type 2 diabetes study of LY3457263
Where: Scottdale
What: Tests whether an investigational medicine from Lilly, LY3457263, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes, BMI 27+.
Call the site: 724-220-5281Study record on ClinicalTrials.gov
Frontier Clinical Research, LLC, Scottdale. 724-220-5281
Type 2 diabetes study of UBT251
Where: Uniontown
What: Tests whether an investigational medicine from Novo Nordisk, UBT251, can help people with type 2 diabetes lower blood sugar.
Free to join
Who can join: Adults 18 to 75 with type 2 diabetes.
Study record on ClinicalTrials.gov
Preferred Primary Care Physicians, Inc., Uniontown
Other GLP-1 studies in Pennsylvania (18)
Fatty liver disease with liver scarring study of survodutide
Where: Flourtown, Hershey, Lancaster and 2 more cities
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (also called MASH or NASH) with liver scarring (fibrosis).
Call the site: 833-602-2368Study record on ClinicalTrials.gov
US Digestive Health, Flourtown. 833-602-2368
Penn State Milton S. Hershey Medical Center, Hershey. 833-602-2368
US Digestive Health, Lancaster. 833-602-2368
Geisinger Health, State College. 833-602-2368
US Digestive Health, Wyomissing. 833-602-2368
Fatty liver disease (also called MASH or NASH) study of survodutide
Where: Flourtown, Hershey, Lancaster and 1 more city
What: Tests whether a GLP-1 and glucagon medicine from Boehringer Ingelheim, survodutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (also called MASH or NASH), BMI 25+.
Call the site: 833-602-2368Study record on ClinicalTrials.gov
US Digestive Health, Flourtown. 833-602-2368
Penn State Milton S. Hershey Medical Center, Hershey. 833-602-2368
US Digestive Health, Lancaster. 833-602-2368
US Digestive Health, Wyomissing. 833-602-2368
Fatty liver disease (MASLD) study of retatrutide
Where: Flourtown, Philadelphia and Wyomissing
What: Tests whether a GLP-1, GIP and glucagon medicine from Lilly, retatrutide, can help people reduce liver fat.
Free to join
Who can join: Adults 18+ with fatty liver disease (MASLD), BMI 25+.
Call the site: 215-664-4362Study record on ClinicalTrials.gov
US Digestive Health - Flourtown, Flourtown. 215-664-4362
Penn Medicine: University of Pennsylvania Health System, Philadelphia
US Digestive Health - Wyomissing, Wyomissing. 610-374-4401
Show 15 more studies
Stress urinary incontinence (bladder leaks) study of orforglipron
Where: Erie and Philadelphia
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people reduce bladder leaks.
Free to join
Who can join: Adults 18+, women only with stress urinary incontinence (bladder leaks), BMI 27+.
Call the site: 215-676-6696Study record on ClinicalTrials.gov
OB/GYN Associates of Erie, Erie
Clinical Research of Philadelphia, Philadelphia. 215-676-6696
Alcohol use disorder study of semaglutide
Where: Philadelphia
What: Tests whether a GLP-1 medicine, semaglutide, can help people with alcohol use disorder drink less.
Free to join
Who can join: Adults 18 to 80 with alcohol use disorder, BMI 21+.
Call the site: 2158235800Study record on ClinicalTrials.gov
Corporal Michael J. Crescenz VA Medical Center, Philadelphia. 2158235800
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia. (215) 823-5894
Prehypertension study of orforglipron
Where: Media and West Chester
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people with prediabetes lose weight.
Free to join
Who can join: Adults 18+ who are overweight, BMI 25+.
Call the site: 610-872-8501Study record on ClinicalTrials.gov
Clinical Renal Associates Ltd., Media. 610-872-8501
Suburban Research Associates, West Chester
Ulcerative colitis study of tirzepatide
Where: Philadelphia
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with ulcerative colitis calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with ulcerative colitis, BMI 27+.
Call the site: 215-955-8900Study record on ClinicalTrials.gov
Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia. 215-955-8900
Crohn's disease study of tirzepatide
Where: Philadelphia
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people with Crohn's disease calm gut inflammation.
Free to join
Who can join: Adults 18 to 70 with Crohn's disease, BMI 27+.
Call the site: 215-955-8900Study record on ClinicalTrials.gov
Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia. 215-955-8900
Peripheral artery disease study of orforglipron
Where: Camp Hill
What: Tests whether a GLP-1 medicine from Lilly, orforglipron, can help people improve blood flow in the legs.
Free to join
Who can join: Adults 18+ with peripheral artery disease (poor blood flow in the legs), BMI 23+.
Call the site: 717-441-1725Study record on ClinicalTrials.gov
Capital Area Research, LLC, Camp Hill. 717-441-1725
ASCVD study of semaglutide
Where: Danville and Philadelphia
What: Tests whether a GLP-1 medicine, semaglutide, can help people lower blood sugar.
Free to join
Who can join: Adults 40 to 80 with type 2 diabetes.
Call the site: 1-866-219-5148, Option 2Study record on ClinicalTrials.gov
Geisinger Medical Center, Danville. 1-866-219-5148, Option 2
Temple University Lewis Katz School of Medicine, Philadelphia. 267-225-4836
Psoriasis study of tirzepatide
Where: Plymouth Meeting
What: Tests whether a GLP-1 and GIP medicine from Lilly, tirzepatide, can help people calm psoriasis.
Free to join
Who can join: Adults 18+ with psoriasis, BMI 27+.
Study record on ClinicalTrials.gov
Dermatology Associates of Plymouth Meeting, Plymouth Meeting
Melanoma study of nivolumab or pembrolizumab
Where: Pittsburgh
What: Tests nivolumab or pembrolizumab in people with melanoma.
Free to join
Who can join: Adults 18+ with melanoma.
Call the site: 412-623-8963Study record on ClinicalTrials.gov
UPMC Hillman Cancer Center, Pittsburgh. 412-623-8963
Cystic fibrosis study of dulaglutide
Where: Philadelphia
What: Tests whether a GLP-1 medicine, dulaglutide, can help people with cystic fibrosis lower blood sugar.
Free to join
Who can join: Adults 18+ with cystic fibrosis, BMI 19+.
Call the site: 215-746-2081Study record on ClinicalTrials.gov
University of Pennsylvania, Philadelphia. 215-746-2081
Opioid use disorder study of semaglutide
Where: Harrisburg
What: Tests whether a GLP-1 medicine, semaglutide, can help people with opioid use disorder cut down on opioids.
Free to join
Who can join: Adults 18 to 75 with opioid use disorder, BMI 18+.
Call the site: (717) 683-7838Study record on ClinicalTrials.gov
Pennsylvania Psychiatric Institute, Harrisburg. (717) 683-7838
Mild autonomous cortisol secretion (MACS) study of tirzepatide
Where: Pittsburgh
What: Tests a GLP-1 and GIP medicine, tirzepatide, in people with mild autonomous cortisol secretion (MACS).
Free to join
Who can join: Adults 18+ with mild autonomous cortisol secretion (MACS), BMI 27+.
Study record on ClinicalTrials.gov
University of Pittsburgh Medical Center, Pittsburgh
Interstitial lung disease study of semaglutide
Where: Philadelphia
What: Tests whether a GLP-1 medicine, semaglutide, can help people with interstitial lung disease lose weight.
Free to join
Who can join: Adults 18 to 80 with obesity, BMI 30+.
Study record on ClinicalTrials.gov
University of Pennsylvania Perelman School of Medicine, Philadelphia
Cystic fibrosis study
Where: Philadelphia
What: A study in people with cystic fibrosis.
Free to join
Who can join: Adults 18+ with cystic fibrosis.
Call the site: 215-746-2081Study record on ClinicalTrials.gov
Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia. 215-746-2081
Diabetic kidney disease study
Where: Philadelphia
What: Tests whether a study medicine, Sodium-glucose cotransporter 2 inhibitors (SGLT2i), can help people with diabetic kidney disease protect their kidneys.
Free to join
Who can join: Adults 18+ with diabetic kidney disease.
Call the site: 2673030158Study record on ClinicalTrials.gov
Penn Presbyterian Medical Center, Philadelphia. 2673030158
Source: ClinicalTrials.gov, the federal registry, read October 16, 2026. Open a study's registry record before you call: it can close to new participants at any time. GLP Chart does not enroll anyone, is not paid for clinical-trial referrals and has no relationship with any sponsor or site on this page.
Clinical trials by state
Every state with a GLP-1 study recruiting today. 48 of them.
- Alabama (18)
- Arizona (22)
- Arkansas (5)
- California (53)
- Colorado (18)
- Connecticut (14)
- Delaware (1)
- District of Columbia (1)
- Florida (43)
- Georgia (23)
- Hawaii (6)
- Idaho (12)
- Illinois (30)
- Indiana (20)
- Iowa (10)
- Kansas (14)
- Kentucky (18)
- Louisiana (14)
- Maine (1)
- Maryland (25)
- Massachusetts (20)
- Michigan (21)
- Minnesota (19)
- Mississippi (7)
- Missouri (22)
- Montana (3)
- Nebraska (7)
- Nevada (11)
- New Hampshire (3)
- New Jersey (11)
- New Mexico (5)
- New York (30)
- North Carolina (31)
- North Dakota (5)
- Ohio (31)
- Oklahoma (12)
- Oregon (5)
- Pennsylvania (33)
- Rhode Island (5)
- South Carolina (25)
- South Dakota (2)
- Tennessee (27)
- Texas (56)
- Utah (14)
- Virginia (28)
- Washington (24)
- West Virginia (5)
- Wisconsin (7)