Missed a GLP-1 dose? The window is 4 days on tirzepatide and 5 on Ozempic
Every GLP-1 label answers the missed-dose question and the answers do not match. Zepbound and Mounjaro give you 4 days (96 hours) to take it. Ozempic gives you 5 days. Wegovy states its rule backwards from the others: take it if the next scheduled dose is more than 2 days away, skip it if it is less. The daily products say skip it and take the next one tomorrow.
Every label's window in one table
| Drug | The label's missed-dose rule | Moving your dosing day |
|---|---|---|
| Wegovy injection | Take it if the next scheduled dose is more than 2 days away. Skip it if the next dose is less than 2 days away, and resume on the regular day. | The label says the time of day and the injection site can change without a dosage modification. |
| Wegovy tablets | Skip the missed dose and take the next one the following day. | Daily dosing. The label requires an empty stomach in the morning with up to 4 ounces of water and nothing else, then a 30 minute wait before food, other drinks or other oral medicines. |
| Zepbound | Within 4 days (96 hours), take it. Past 4 days, skip it and take the next dose on the regular day. | Allowed if at least 3 days (72 hours) separate the two doses. |
| Mounjaro | Within 4 days (96 hours), take it. Past 4 days, skip it and take the next dose on the regular day. | Allowed if at least 3 days (72 hours) separate the two doses. |
| Ozempic injection | Within 5 days, take it. Past 5 days, skip it and take the next dose on the regular day. | Allowed if at least 2 days, more than 48 hours, separate the two doses. |
| Saxenda | Resume the once-daily regimen at the next scheduled dose. Do not take an extra dose or a bigger one to catch up. | Daily dosing, so the question does not arise. |
| Rybelsus | Skip the missed dose and take the next one the following day. | Daily dosing. The label requires an empty stomach in the morning with up to 4 ounces of water and nothing else. |
A longer gap is a different question
Missing several weeks is common, whether a pharmacy ran dry or a prior authorization lapsed. Wegovy and Saxenda are the only labels that tell the prescriber what to do about it.
- Wegovy. If 2 or more consecutive doses are missed, the label says to reinitiate dosage escalation at a lower dosage, to reduce the risk of gastrointestinal adverse reactions. It does not name which lower dosage, so that part is the prescriber's judgment.
- Saxenda. The strictest of the six. More than three days since the last dose and the label says to restart at 0.6 mg daily and climb the whole table again.
- Zepbound, Mounjaro, Ozempic and Rybelsus. Silent. We searched the full structured product labels for every form of reinitiate, re-escalate, restart and interruption and found nothing. A restart protocol for tirzepatide comes from clinical practice, because the label does not contain one.
If the gap was about money
A missed month is often a billing problem. The chart prices every program at its ongoing maintenance cost, so you can see what continuing would cost before the next refill lands.
Compare every program at its maintenance price →
Which programs let you pause or cancel without a fee →
Frequently asked questions
How late can I take a missed Zepbound or Mounjaro dose?
Within 4 days, which both labels write as 96 hours. Past 4 days, skip it and take the next dose on the regularly scheduled day.
How late can I take a missed Ozempic dose?
Within 5 days. Past 5 days, skip it and take the next dose on the regular day.
Why is the Wegovy rule written differently?
It is keyed to the next dose rather than the missed one. Take the missed injection if the next scheduled dose is more than 2 days away, and skip it if the next dose is less than 2 days away.
What if I have missed several weeks?
Two of the six labels answer that and four do not. Wegovy says to reinitiate dosage escalation at a lower dosage after 2 or more consecutive missed doses, without naming which. Saxenda says more than three days off and you restart at 0.6 mg. Zepbound, Mounjaro, Ozempic and Rybelsus say nothing about it, so a restart plan for those comes from your prescriber and not from a label.
Can I change which day I inject?
Zepbound and Mounjaro allow it if at least 3 days, 72 hours, separate the two doses. Ozempic allows it if at least 2 days, more than 48 hours, separate them. Wegovy's label says the time of day and the injection site can both change without a dosage modification.
Every sentence in these labels is addressed to a prescriber. If you are unsure which window applies to what you were dispensed, or you have missed more than one dose, call the program or the pharmacy before you inject anything.
Sources
Evidence checked August 31, 2026
Each clinical claim above links to the document it came from, so you can read the source instead of trusting us. GLP Chart has no medical reviewer, and does not borrow a name for one. What that means.
- The Wegovy missed-dose rule for the injection and the tablet, the reinitiation sentence after 2 or more missed doses, and the sentence on changing the time of day and the injection siteFDA prescribing information for Wegovy, injection and tablets (DailyMed, revised June 2026)
- The Zepbound 96-hour missed-dose window and the 72-hour rule for moving the dosing dayFDA prescribing information for Zepbound (DailyMed, revised August 2026)
- The Mounjaro 96-hour missed-dose window and the 72-hour rule for moving the dosing dayFDA prescribing information for Mounjaro (DailyMed, revised August 2026)
- The Ozempic five-day missed-dose window and the 48-hour rule for moving the dosing dayFDA prescribing information for Ozempic injection (DailyMed, revised June 2026)
- The Saxenda missed-dose instruction and its three-day restart ruleFDA prescribing information for Saxenda (DailyMed, revised February 2026)
- The Rybelsus missed-dose instructionFDA prescribing information for Rybelsus and Ozempic tablets (DailyMed)
