What is GLP-1 titration?
Titration means raising a GLP-1 dose in steps, usually every four weeks, until you reach the dose you stay on. It exists to limit nausea and other stomach side effects.
The labelled steps
Wegovy pens go 0.25, 0.5, 1, 1.7, then 2.4 mg. Zepbound starts at 2.5 mg and adds 2.5 mg every four weeks, up to as much as 15 mg. A prescriber can hold a step longer if side effects are strong.
Two cash programs to check.
No insurance needed.
- Check price →
- Check price →SnagRx's homepage shows its 12-month prepaid prices first
What it means for the price
Many programs and both brand pharmacies charge more for higher doses. LillyDirect prices Zepbound vials by dose, and some compounded programs raise the monthly price at higher doses. The chart's dose pages show the price at each step.
Questions
How long does GLP-1 titration take?
On the labelled schedules it takes about four to five months to reach the top Wegovy or Zepbound dose.
Sources
Prices on GLP Chart are read from each program's own pricing page. How: how we check prices. Every program's price this month: the GLP-1 price index.