Checked October 27, 2026
Zepbound 5mg costs $399 a month from LillyDirect
Zepbound 5mg costs $399 a month from LillyDirect, the same for 4 single-dose vials or 1 KwikPen.
There is no refill window at 5mg: the price holds whenever you reorder. The 45-day rule starts at 7.5mg.
Lilly says "2.5 mg is a starting dose and is not approved as a maintenance dose." 5mg is the first dose past it.
| Form | A month | A month is | Where |
|---|---|---|---|
| Single-dose vial | $399 | 4 single-dose vials, 28 days | LillyDirect only, self-pay only |
| KwikPen | $399 | 1 four-dose KwikPen, 28 days | LillyDirect, self-pay |
Source: LillyDirect's Zepbound page, checked October 27, 2026. How we check.
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Cash programs to check if LillyDirect's price is more than you want to pay.
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What a year of 5mg costs
Lilly counts a month as 28 days, so a year is 13 fills. At $399 a fill that is $5,187 a year.
Who else sells the 5mg KwikPen
Sam's Club Member Health charges $399 a month for the 5mg KwikPen, and a Sam's Club membership is extra.
Walgreens Weight Management charges $448 a month for the 5mg KwikPen: $399 for the pen plus $49 in its own fees.
Sesame Care charges $498 a month for the 5mg KwikPen: $399 for the pen plus $99 in its own fees.
Ro Body charges $548 a month for the 5mg KwikPen: $399 for the pen plus $149 in its own fees.
At other pharmacies, Lilly's savings card is a separate offer. Its price at 7.5mg and up is for the KwikPen only, and the card expires December 31, 2026.
Questions
How much is Zepbound 5mg through LillyDirect?
$399 a month, for 4 single-dose vials or 1 KwikPen. Read on LillyDirect's Zepbound page on October 27, 2026.
Is the 5mg vial cheaper than the 5mg KwikPen?
No. LillyDirect charges $399 a month for either.
Do I have to refill within 45 days at 5mg?
No. The 45 days refill price applies at 7.5mg and up. At 5mg the price is $399 either way.
How much does a year of Zepbound 5mg cost?
$5,187: 13 fills of 28 days at $399 each.
Related prices
- Every Zepbound price
- Zepbound dose steps
- LillyDirect prices and how to order
- Zepbound KwikPen cost by dose
- Zepbound 2.5mg cost
- Zepbound 7.5mg cost
- Zepbound 10mg to 15mg cost
- Zepbound vial cost
This page compares published prices. No clinician reviewed it, and it is not medical advice. GLP Chart is not a medical provider.