Prices verified June 22, 2026
Head-to-head

Knownwell vs Strut Health: GLP-1 weight loss comparison 2026

Strut Health comes out ahead overall (7.2 vs 6.9/10). The right pick still depends on your situation.

Knownwell
Knownwell logo
Score: 6.9 out of 10
6.9
out of 10
Primary care plus obesity medicine in one insured practice.
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Strut HealthOur pick
Strut Health logo
Score: 7.2 out of 10
7.2
out of 10
Needle-free entry dose for patients avoiding injections.
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Quick verdict

Strut Health is the better pick for most patients on overall scoring. One of the cheapest legitimate compounded options in the US market thanks to a niche oral lozenge format. No membership fee, free shipping, free consults and physician access included. Trade-off: lozenge bioavailability data is thin compared to standard injectable semaglutide.

That said, Knownwell wins on specific dimensions. Knownwell is the most clinically credentialed name in the new wave: hybrid clinics plus telehealth, founded by a Harvard obesity-medicine physician. Insurance-led model. The opposite of cash-pay compounded culture, and proud of it.

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Side-by-side

KnownwellStrut Health
Starts fromInsurance-billed (+ med separate)$149/mo entry dose (injectable semaglutide) (incl. medication)
Monthly cost gapStrut Health is $100/mo cheaper than Knownwell
Lock-inMonth-to-monthMonth-to-month
Time to prescription14 days3 days
Consultation typeLiveAsync
Affiliate networkDirectDirect

Score by dimension

Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.

KnownwellStrut Health
Pricing transparency5/109/10
Cancellation terms7/109/10
Onboarding experience5/107/10
Medication options8/104/10
Member reviews9.4/106.8/10

When to choose Knownwell

Best for primary-care integration

Patients with strong insurance who want primary care plus obesity medicine in one practice.

Knownwell wins on medication options, member reviews on the dimensional scoring. The caveat: Cash-pay-only buyers, uninsured patients or anyone who wants async-only care.

When to choose Strut Health

Best for oral semaglutide entry

Cost-sensitive patients who want needle-free GLP-1 entry under $100/mo and don't mind a less-studied delivery format.

Strut Health wins on pricing transparency, cancellation terms, onboarding experience and runs $100/mo cheaper than Knownwell at the entry tier ($199 vs $299). Over a year that's $1,200 you keep. The caveat: Anyone who wants brand-name FDA-approved semaglutide or insurance-billed care. Note also: Compounded semaglutide is not FDA-approved

If cost is your main filter

Strut Health is the cheaper monthly: $199 all-in vs $299 for Knownwell. That's $100 a month or $1,200a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $300 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.

If lock-in is your main filter

Knownwell (month-to-month) and Strut Health (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.

FAQ

Is Knownwell cheaper than Strut Health?
Knownwell starts at Insurance-billed (plus medication). Strut Health starts at $149/mo entry dose (injectable semaglutide) (medication included). The cheaper option depends on whether you have insurance coverage for branded GLP-1s.
Can I switch from Knownwell to Strut Health mid-treatment?
Yes. Both programs accept new patients on existing GLP-1 doses. Bring your current prescription details to the new program's intake. Your titration schedule typically continues from where it left off.
Which program has better member feedback?
Knownwell scored 9.4/10 on member reviews; Strut Health scored 6.8/10. This pillar is each program's public Trustpilot rating mapped to a 0-10 score. Read Knownwell's feedback section or Strut Health's feedback section for the details.

Read the full reviews

All head-to-head comparisons → · Full chart → · Cost guide · Programs guide

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. We never remove unfavorable information at an advertiser's request. Pricing is pulled from each program's public-facing page every Monday.