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Quick verdict
Sesame Care is the better pick for most patients on overall scoring. Sesame is a cash-pay marketplace, not a program. Pay one fee, see one doctor, leave with a script. Cheapest path to a real branded GLP-1 prescription if you can fill it elsewhere. Zero ongoing care. That is the point and the limit.
That said, Costco / Success by Sesame wins on specific dimensions. Costco bundles Success by Sesame care with discounted self-pay branded GLP-1 at Costco Pharmacy. The medication price is genuinely low for a brand-name pen: the Wegovy or Ozempic injection is $349/mo self-pay, with care from $59/mo on the annual plan. The catch is a paid Costco membership, and the bundle has no member outcome record yet.
Side-by-side
| Sesame Care | Costco / Success by Sesame | |
|---|---|---|
| Starts from | $189/mo (+ med separate) | $408/mo (incl. medication) |
| Monthly cost gap | Costco / Success by Sesame is $21/mo cheaper than Sesame Care | |
| Lock-in | Month-to-month | Month-to-month |
| Time to prescription | 1 day | 2 days |
| Consultation type | Live | Video |
| Affiliate network | CJ | CJ |
Score by dimension
Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.
| Sesame Care | Costco / Success by Sesame | |
|---|---|---|
| Pricing transparency | 8/10 | 7/10 |
| Cancellation terms | 10/10 | 8/10 |
| Onboarding experience | 8/10 | 7/10 |
| Medication options | 6/10 | 7/10 |
| Member reviews | 9/10 | 9/10 |
When to choose Sesame Care
Best for one-off self-directed Rx
Self-directed buyers who want a one-off prescription and will manage refills, sourcing and titration on their own.
Sesame Care wins on pricing transparency, cancellation terms, onboarding experience on the dimensional scoring. The caveat: Anyone wanting coaching, dietitian access, ongoing accountability or an integrated medication supply chain.
When to choose Costco / Success by Sesame
Best for Costco members
Existing Costco members who want discounted self-pay branded GLP-1 with light telehealth care attached.
Costco / Success by Sesame wins on medication options and runs $21/mo cheaper than Sesame Care at the entry tier ($208 vs $229). Over a year that's $252 you keep. The caveat: Anyone who is not a Costco member, wants a compounded option, or wants a long member-review track record.
If cost is your main filter
Costco / Success by Sesame is the cheaper monthly: $208 all-in vs $229 for Sesame Care. That's $21 a month or $252a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $63 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.
If lock-in is your main filter
Sesame Care (month-to-month) and Costco / Success by Sesame (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.
FAQ
Is Sesame Care cheaper than Costco / Success by Sesame?
Can I switch from Sesame Care to Costco / Success by Sesame mid-treatment?
Which program has better member feedback?
Read the full reviews
All head-to-head comparisons → · Full chart → · Cost guide · Programs guide
