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Quick verdict
Henry Meds is the better pick for most patients on overall scoring. Henry built the cash-pay compounded GLP-1 category and still runs the cleanest version of it. Predictable bundled pricing and true month-to-month terms, though the semaglutide tiers moved behind signup in June 2026. Pivoted hard after the FDA shortage delisting and now leans on personalization-claim 503A pharmacies.
That said, PlushCare wins on specific dimensions. PlushCare is a primary-care telehealth platform that happens to prescribe GLP-1s, not a GLP-1 specialist. That distinction makes it the strongest pick for the insured and the most expensive for everyone else.
Side-by-side
| PlushCare | Henry Meds | |
|---|---|---|
| Starts from | $19.99/mo (+ med separate) | $297/mo (incl. medication) |
| Monthly cost gap | Henry Meds is $369/mo cheaper than PlushCare | |
| Lock-in | Month-to-month | Month-to-month |
| Time to prescription | 1 day | 2 days |
| Consultation type | Live | Asynchronous |
| Affiliate network | Impact | Impact |
Score by dimension
Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.
| PlushCare | Henry Meds | |
|---|---|---|
| Pricing transparency | 5/10 | 8/10 |
| Cancellation terms | 7/10 | 9/10 |
| Onboarding experience | 9/10 | 8/10 |
| Medication options | 7/10 | 6/10 |
| Member reviews | 6.8/10 | 9/10 |
When to choose PlushCare
Best for insurance-covered branded
Patients with commercial insurance that covers Wegovy or Zepbound. PlushCare's PCPs handle prior authorization paperwork well.
PlushCare wins on onboarding experience, medication options on the dimensional scoring. The caveat: Cash-pay patients comparing on monthly cost. The membership + visit fees + cash medication math is rarely competitive against specialists.
When to choose Henry Meds
Best for cheapest compounded
Buyers who want predictable flat-rate compounded semaglutide with no commitments and minimal friction.
Henry Meds wins on pricing transparency, cancellation terms, member reviews and runs $369/mo cheaper than PlushCare at the entry tier ($179 vs $548). Over a year that's $4,428 you keep. The caveat: Patients who want branded Wegovy or Zepbound through insurance, or who want a high-touch coaching program. Note also: Subject of ongoing scrutiny over personalization-claim compounding post-shortage delisting (FDA Feb 2025).
If cost is your main filter
Henry Meds is the cheaper monthly: $179 all-in vs $548 for PlushCare. That's $369 a month or $4,428a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $1107 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.
If lock-in is your main filter
PlushCare (month-to-month) and Henry Meds (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.
FAQ
Is PlushCare cheaper than Henry Meds?
Can I switch from PlushCare to Henry Meds mid-treatment?
Which program has better member feedback?
Read the full reviews
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