Prices verified June 22, 2026
Head-to-head

Medvi vs Sesame Care: GLP-1 weight loss comparison 2026

Sesame Care comes out ahead overall (8.2 vs 7.8/10). The right pick still depends on your situation.

Medvi
Medvi logo
Score: 7.8 out of 10
7.8
out of 10
Flat refill price that holds as your dose climbs.
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Sesame CareOur pick
Sesame Care logo
Score: 8.2 out of 10
8.2
out of 10
Pay-per-visit care with medication sold near wholesale.
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Quick verdict

Sesame Care is the better pick for most patients on overall scoring. Sesame is a cash-pay marketplace, not a program. Pay one fee, see one doctor, leave with a script. Cheapest path to a real branded GLP-1 prescription if you can fill it elsewhere. Zero ongoing care. That is the point and the limit.

That said, Medvi wins on specific dimensions. Medvi runs a compounded-semaglutide and tirzepatide model at flat monthly pricing, with no lock-in and rapid intake. Comparable to Henry Meds and Mochi on price; less established clinical depth than Form Health or Knownwell. Best fit for cash-pay patients who want predictable monthly cost with minimal friction.

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Side-by-side

MedviSesame Care
Starts from$299/mo (incl. medication)$189/mo (+ med separate)
Monthly cost gapMedvi is $50/mo cheaper than Sesame Care
Lock-inMonth-to-monthMonth-to-month
Time to prescription2 days1 day
Consultation typeAsynchronousLive
Affiliate networkDirectCJ

Score by dimension

Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.

MedviSesame Care
Pricing transparency8/108/10
Cancellation terms8/1010/10
Onboarding experience7/108/10
Medication options7/106/10
Member reviews9/109/10

When to choose Medvi

Best for flat compounded with no lock-in

Cash-pay patients who want flat predictable compounded GLP-1 pricing with no lock-in and same-week onboarding. Strong fit if you've taken GLP-1 before and want a simple ongoing prescription channel.

Medvi wins on medication options and runs $50/mo cheaper than Sesame Care at the entry tier ($179 vs $229). Over a year that's $600 you keep. The caveat: Insurance-pathway shoppers, patients with multiple comorbidities needing clinical depth or anyone wanting branded Wegovy or Zepbound through standard PA. Note also: Compounded GLP-1 carries 503A regulatory exposure; see compounded callout

When to choose Sesame Care

Best for one-off self-directed Rx

Self-directed buyers who want a one-off prescription and will manage refills, sourcing and titration on their own.

Sesame Care wins on cancellation terms, onboarding experience on the dimensional scoring. The caveat: Anyone wanting coaching, dietitian access, ongoing accountability or an integrated medication supply chain.

If cost is your main filter

Medvi is the cheaper monthly: $179 all-in vs $229 for Sesame Care. That's $50 a month or $600a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $150 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.

If lock-in is your main filter

Medvi (month-to-month) and Sesame Care (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.

FAQ

Is Medvi cheaper than Sesame Care?
Medvi starts at $299/mo (medication included). Sesame Care starts at $189/mo (plus medication). The cheaper option depends on whether you have insurance coverage for branded GLP-1s.
Can I switch from Medvi to Sesame Care mid-treatment?
Yes. Both programs accept new patients on existing GLP-1 doses. Bring your current prescription details to the new program's intake. Your titration schedule typically continues from where it left off.
Which program has better member feedback?
Medvi scored 9/10 on member reviews; Sesame Care scored 9/10. This pillar is each program's public Trustpilot rating mapped to a 0-10 score. Read Medvi's feedback section or Sesame Care's feedback section for the details.

Read the full reviews

All head-to-head comparisons → · Full chart → · Cost guide · Programs guide

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. We never remove unfavorable information at an advertiser's request. Pricing is pulled from each program's public-facing page every Monday.