Prices verified June 22, 2026
Head-to-head

Medvi vs Knownwell: GLP-1 weight loss comparison 2026

Medvi comes out ahead overall (7.8 vs 6.9/10). The right pick still depends on your situation.

MedviOur pick
Medvi logo
Score: 7.8 out of 10
7.8
out of 10
Flat refill price that holds as your dose climbs.
Visit Medvi
Knownwell
Knownwell logo
Score: 6.9 out of 10
6.9
out of 10
Primary care plus obesity medicine in one insured practice.
Visit Knownwell

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Quick verdict

Medvi is the better pick for most patients on overall scoring. Medvi runs a compounded-semaglutide and tirzepatide model at flat monthly pricing, with no lock-in and rapid intake. Comparable to Henry Meds and Mochi on price; less established clinical depth than Form Health or Knownwell. Best fit for cash-pay patients who want predictable monthly cost with minimal friction.

That said, Knownwell wins on specific dimensions. Knownwell is the most clinically credentialed name in the new wave: hybrid clinics plus telehealth, founded by a Harvard obesity-medicine physician. Insurance-led model. The opposite of cash-pay compounded culture, and proud of it.

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Side-by-side

MedviKnownwell
Starts from$299/mo (incl. medication)Insurance-billed (+ med separate)
Monthly cost gapMedvi is $120/mo cheaper than Knownwell
Lock-inMonth-to-monthMonth-to-month
Time to prescription2 days14 days
Consultation typeAsynchronousLive
Affiliate networkDirectDirect

Score by dimension

Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.

MedviKnownwell
Pricing transparency8/105/10
Cancellation terms8/107/10
Onboarding experience7/105/10
Medication options7/108/10
Member reviews9/109.4/10

When to choose Medvi

Best for flat compounded with no lock-in

Cash-pay patients who want flat predictable compounded GLP-1 pricing with no lock-in and same-week onboarding. Strong fit if you've taken GLP-1 before and want a simple ongoing prescription channel.

Medvi wins on pricing transparency, cancellation terms, onboarding experience and runs $120/mo cheaper than Knownwell at the entry tier ($179 vs $299). Over a year that's $1,440 you keep. The caveat: Insurance-pathway shoppers, patients with multiple comorbidities needing clinical depth or anyone wanting branded Wegovy or Zepbound through standard PA. Note also: Compounded GLP-1 carries 503A regulatory exposure; see compounded callout

When to choose Knownwell

Best for primary-care integration

Patients with strong insurance who want primary care plus obesity medicine in one practice.

Knownwell wins on medication options, member reviews on the dimensional scoring. The caveat: Cash-pay-only buyers, uninsured patients or anyone who wants async-only care.

If cost is your main filter

Medvi is the cheaper monthly: $179 all-in vs $299 for Knownwell. That's $120 a month or $1,440a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $360 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.

If lock-in is your main filter

Medvi (month-to-month) and Knownwell (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.

FAQ

Is Medvi cheaper than Knownwell?
Medvi starts at $299/mo (medication included). Knownwell starts at Insurance-billed (plus medication). The cheaper option depends on whether you have insurance coverage for branded GLP-1s.
Can I switch from Medvi to Knownwell mid-treatment?
Yes. Both programs accept new patients on existing GLP-1 doses. Bring your current prescription details to the new program's intake. Your titration schedule typically continues from where it left off.
Which program has better member feedback?
Medvi scored 9/10 on member reviews; Knownwell scored 9.4/10. This pillar is each program's public Trustpilot rating mapped to a 0-10 score. Read Medvi's feedback section or Knownwell's feedback section for the details.

Read the full reviews

All head-to-head comparisons → · Full chart → · Cost guide · Programs guide

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. We never remove unfavorable information at an advertiser's request. Pricing is pulled from each program's public-facing page every Monday.