Prices verified June 22, 2026
Head-to-head

Hone Health vs Costco / Success by Sesame: GLP-1 weight loss comparison 2026

Costco / Success by Sesame comes out ahead overall (7.6 vs 7.3/10). The right pick still depends on your situation.

Hone Health
Hone Health logo
Score: 7.3 out of 10
7.3
out of 10
Men's hormone program that pairs GLP-1 with TRT.
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Costco / Success by SesameOur pick
Costco / Success by Sesame logo
Score: 7.6 out of 10
7.6
out of 10
Discounted member care plus brand-name medication at Costco.
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Quick verdict

Costco / Success by Sesame is the better pick for most patients on overall scoring. Costco bundles Success by Sesame care with discounted self-pay branded GLP-1 at Costco Pharmacy. The medication price is genuinely low for a brand-name pen: the Wegovy or Ozempic injection is $349/mo self-pay, with care from $59/mo on the annual plan. The catch is a paid Costco membership, and the bundle has no member outcome record yet.

That said, Hone Health wins on specific dimensions. Hone Health targets men's hormone optimization (testosterone, semaglutide, peptides) with an at-home blood-draw model. GLP-1 added in 2024 as part of the metabolic-optimization product line. Strong for the testosterone+GLP-1 stack; less obesity-medicine depth than Form Health.

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Side-by-side

Hone HealthCostco / Success by Sesame
Starts from$185/mo (+ med separate)$408/mo (incl. medication)
Monthly cost gapHone Health is $23/mo cheaper than Costco / Success by Sesame
Lock-inMonth-to-monthMonth-to-month
Time to prescription7 days2 days
Consultation typeVideoVideo
Affiliate networkDirectCJ

Score by dimension

Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.

Hone HealthCostco / Success by Sesame
Pricing transparency6/107/10
Cancellation terms7/108/10
Onboarding experience7/107/10
Medication options7/107/10
Member reviews9.6/109/10

When to choose Hone Health

Best for men's hormone plus GLP-1 stack

Men interested in combined hormone-optimization and weight loss. Patients who want at-home blood draws and broader metabolic protocols beyond standard obesity care.

Hone Health wins on member reviews and runs $23/mo cheaper than Costco / Success by Sesame at the entry tier ($185 vs $208). Over a year that's $276 you keep. The caveat: Patients seeking obesity-medicine specialization, women's-specific needs or the cheapest cash-pay path. Note also: Hone markets compounded peptides beyond GLP-1; the broader peptide-marketing landscape has higher 2025-2026 regulatory exposure than GLP-1 alone

When to choose Costco / Success by Sesame

Best for Costco members

Existing Costco members who want discounted self-pay branded GLP-1 with light telehealth care attached.

Costco / Success by Sesame wins on pricing transparency, cancellation terms on the dimensional scoring. The caveat: Anyone who is not a Costco member, wants a compounded option, or wants a long member-review track record.

If cost is your main filter

Hone Health is the cheaper monthly: $185 all-in vs $208 for Costco / Success by Sesame. That's $23 a month or $276a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $69 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.

If lock-in is your main filter

Hone Health (month-to-month) and Costco / Success by Sesame (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.

FAQ

Is Hone Health cheaper than Costco / Success by Sesame?
Hone Health starts at $185/mo (plus medication). Costco / Success by Sesame starts at $408/mo (medication included). The cheaper option depends on whether you have insurance coverage for branded GLP-1s.
Can I switch from Hone Health to Costco / Success by Sesame mid-treatment?
Yes. Both programs accept new patients on existing GLP-1 doses. Bring your current prescription details to the new program's intake. Your titration schedule typically continues from where it left off.
Which program has better member feedback?
Hone Health scored 9.6/10 on member reviews; Costco / Success by Sesame scored 9/10. This pillar is each program's public Trustpilot rating mapped to a 0-10 score. Read Hone Health's feedback section or Costco / Success by Sesame's feedback section for the details.

Read the full reviews

All head-to-head comparisons → · Full chart → · Cost guide · Programs guide

Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. We never remove unfavorable information at an advertiser's request. Pricing is pulled from each program's public-facing page every Monday.