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Quick verdict
Henry Meds is the better pick for most patients on overall scoring. Henry built the cash-pay compounded GLP-1 category and still runs the cleanest version of it. Predictable bundled pricing and true month-to-month terms, though the semaglutide tiers moved behind signup in June 2026. Pivoted hard after the FDA shortage delisting and now leans on personalization-claim 503A pharmacies.
That said, Costco / Success by Sesame wins on specific dimensions. Costco bundles Success by Sesame care with discounted self-pay branded GLP-1 at Costco Pharmacy. The medication price is genuinely low for a brand-name pen: the Wegovy or Ozempic injection is $349/mo self-pay, with care from $59/mo on the annual plan. The catch is a paid Costco membership, and the bundle has no member outcome record yet.
Side-by-side
| Henry Meds | Costco / Success by Sesame | |
|---|---|---|
| Starts from | $297/mo (incl. medication) | $408/mo (incl. medication) |
| Monthly cost gap | Henry Meds is $29/mo cheaper than Costco / Success by Sesame | |
| Lock-in | Month-to-month | Month-to-month |
| Time to prescription | 2 days | 2 days |
| Consultation type | Asynchronous | Video |
| Affiliate network | Impact | CJ |
Score by dimension
Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.
| Henry Meds | Costco / Success by Sesame | |
|---|---|---|
| Pricing transparency | 8/10 | 7/10 |
| Cancellation terms | 9/10 | 8/10 |
| Onboarding experience | 8/10 | 7/10 |
| Medication options | 6/10 | 7/10 |
| Member reviews | 9/10 | 9/10 |
When to choose Henry Meds
Best for cheapest compounded
Buyers who want predictable flat-rate compounded semaglutide with no commitments and minimal friction.
Henry Meds wins on pricing transparency, cancellation terms, onboarding experience and runs $29/mo cheaper than Costco / Success by Sesame at the entry tier ($179 vs $208). Over a year that's $348 you keep. The caveat: Patients who want branded Wegovy or Zepbound through insurance, or who want a high-touch coaching program. Note also: Subject of ongoing scrutiny over personalization-claim compounding post-shortage delisting (FDA Feb 2025).
When to choose Costco / Success by Sesame
Best for Costco members
Existing Costco members who want discounted self-pay branded GLP-1 with light telehealth care attached.
Costco / Success by Sesame wins on medication options on the dimensional scoring. The caveat: Anyone who is not a Costco member, wants a compounded option, or wants a long member-review track record.
If cost is your main filter
Henry Meds is the cheaper monthly: $179 all-in vs $208 for Costco / Success by Sesame. That's $29 a month or $348a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $87 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.
If lock-in is your main filter
Henry Meds (month-to-month) and Costco / Success by Sesame (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.
FAQ
Is Henry Meds cheaper than Costco / Success by Sesame?
Can I switch from Henry Meds to Costco / Success by Sesame mid-treatment?
Which program has better member feedback?
Read the full reviews
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