

Quick verdict
Sesame Care is the better pick for most patients on overall scoring. Sesame is a cash-pay marketplace, not a program. Pay one fee, see one doctor, leave with a script. Cheapest path to a real branded GLP-1 prescription if you can fill it elsewhere. Zero ongoing care, which is the point and the limit.
That said, Calibrate wins on specific dimensions. Calibrate is a coaching and insurance-navigation program whose value proposition has weakened as direct-to-consumer pricing from Lilly and Novo undercut the 'we'll handle insurance for you' pitch. Cut its fee from $299 to $199 in 2026.
Side-by-side
| Calibrate | Sesame Care | |
|---|---|---|
| Starts from | $199/mo (+ med separate) | $30/visit (+ med separate) |
| Lock-in | 3-month minimum | Month-to-month |
| Time to prescription | 14 days | 1 day |
| Consultation type | Synchronous | Synchronous |
| Affiliate network | Impact | CJ |
Score by dimension
Five dimensions, ten points each. The winner of each dimension is highlighted.
| Calibrate | Sesame Care | |
|---|---|---|
| Pricing transparency | 5/10 | 8/10 |
| Cancellation terms | 6/10 | 10/10 |
| Onboarding experience | 4/10 | 8/10 |
| Medication options | 7/10 | 6/10 |
| Member outcomes | 3/10 | 5/10 |
When to choose Calibrate
Patients who specifically want behavioral coaching and have insurance that covers branded GLP-1s. Calibrate's clinicians and coaches handle prior authorization paperwork well.
When to choose Sesame Care
Self-directed buyers who want a one-off prescription and will manage refills, sourcing, and titration on their own.
FAQ
Is Calibrate cheaper than Sesame Care?
Can I switch from Calibrate to Sesame Care mid-treatment?
Which program has better member feedback?
Read the full reviews
All head-to-head comparisons → · Full chart →