Humana · SOP con síndrome metabólico · Versión completa en inglés: /pa-letter/humana--pcos/

Carta de PA para Humana: SOP con síndrome metabólico.

Plantilla defensible de carta para Wegovy, Zepbound or off-label Mounjaro depending on T2D status. PCOS is not an FDA-approved indication for GLP-1, but PCOS with documented insulin resistance, prediabetes or obesity qualifies under the obesity or T2D pathways.

La carta misma está en inglés porque el revisor del plan la lee en inglés. La envuelve y la firma su clínico.

Plan
Humana
Commercial / Medicare Advantage / Medicare Part D
Enviar a través de
Humana provider portal, CoverMyMeds or fax 1-877-486-2621
Tiempo de respuesta
72 hours standard, 24 hours expedited
Plazo de apelación
60 days from denial notice (Medicare Part D)
Cita de política: Humana Pharmacy Solutions PA Criteria, GLP-1 Receptor Agonists.
Nota del plan: Humana is one of the largest Medicare Advantage and Part D carriers. Medicare Part D plans cover GLP-1 for T2D (Ozempic, Mounjaro) routinely and for cardiovascular indication (Wegovy under the SELECT label expansion) since 2024. Pure obesity indication is not covered under Medicare statutorily, so Wegovy and Zepbound for obesity require the CV or T2D path on a Medicare plan.

La carta (copiar y editar)

Copie el cuerpo a continuación y péguelo en el portal de su clínico o procesador de textos. Reemplace cada marcador de posición entre [CORCHETES] con datos específicos del paciente antes de enviar. La carta es de su clínico al plan, firmada por su clínico.

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[Today's date]

Humana
Prior Authorization Department
Submitted via: Humana provider portal, CoverMyMeds or fax 1-877-486-2621

Re: Prior Authorization Request, Wegovy, Zepbound or off-label Mounjaro depending on T2D status
Patient: [Patient full name]
Member ID: [Plan member ID]
Date of birth: [Patient DOB]
Group number: [Group number if applicable]
Prescriber: [Prescriber full name, NPI, DEA]
Prescriber contact: [Phone, fax, email]

To the Humana Prior Authorization Reviewer,

I am the treating clinician for [Patient name]. I am writing to request prior authorization for Wegovy, Zepbound or off-label Mounjaro depending on T2D status for treatment of PCOS with metabolic syndrome (ICD-10: E28.2, E66.9, R73.03).

Clinical justification

PCOS itself is not an FDA-approved indication for any GLP-1 receptor agonist, but PCOS frequently coexists with insulin resistance, prediabetes and obesity, each of which is a qualifying indication. This PA pathway requests coverage under the obesity indication (if BMI greater than or equal to 30 or 27 with comorbidity) or under the T2D indication (if A1c greater than or equal to 6.5 percent). PCOS-specific evidence: a 2023 systematic review in Reproductive Sciences pooled GLP-1 trial data in women with PCOS and found significant improvements in BMI, insulin resistance (HOMA-IR) and androgen levels at 12 to 24 weeks of treatment.

Patient-specific findings

  - [Insert current measurements: weight, height, BMI, blood pressure]
  - [Insert relevant lab values with dates: A1c, lipid panel, kidney function]
  - [Insert documentation of comorbidities with ICD-10]
  - [Insert documentation of prior treatment history, including any prior GLP-1 trials, anti-obesity medication trials or lifestyle intervention]

Criteria met per Humana policy

This request meets the criteria set out in Humana Pharmacy Solutions PA Criteria, GLP-1 Receptor Agonists:

  - PCOS diagnosis documented with ICD-10 E28.2 (often confirmed by Rotterdam criteria)
  - Documentation of metabolic complications: insulin resistance, prediabetes (A1c 5.7 to 6.4) or T2D (A1c greater than or equal to 6.5)
  - BMI documented (qualifies under obesity pathway if 30 or above, or 27 with comorbidity)
  - Six-month lifestyle intervention documented for the obesity pathway
  - Endocrinology or reproductive endocrinology consult letter (strengthens but not always required)

Supporting evidence

The clinical case for Wegovy, Zepbound or off-label Mounjaro depending on T2D status in this indication is supported by the following registration trials and outcomes data:

  - Jensterle et al. 2014 (liraglutide in PCOS, Endocrine Connections)
  - Frossing et al. 2018 (liraglutide in PCOS, Diabetes Obesity and Metabolism)
  - Pooled meta-analyses of GLP-1 in PCOS (Reproductive Sciences 2023)

Plan-specific note

Humana is one of the largest Medicare Advantage and Part D carriers. Medicare Part D plans cover GLP-1 for T2D (Ozempic, Mounjaro) routinely and for cardiovascular indication (Wegovy under the SELECT label expansion) since 2024. Pure obesity indication is not covered under Medicare statutorily, so Wegovy and Zepbound for obesity require the CV or T2D path on a Medicare plan.

Requested action

I am requesting prior authorization for Wegovy, Zepbound or off-label Mounjaro depending on T2D status at the [insert starting dose] starting dose, with planned titration per FDA labeling. I am also requesting that this authorization be granted for a continuous 12-month period subject to documented clinical response, per standard formulary practice.

If additional information is required, please contact me directly at [Prescriber phone] or [Prescriber email]. I am available to discuss this case with your medical director if helpful.

Thank you for your attention to this request.

Sincerely,

[Prescriber full signature]
[Prescriber printed name, credentials]
[Prescriber NPI]
[Practice name and address]

Attachments:
  - Current vital signs and BMI calculation
  - Most recent relevant labs
  - Documentation of comorbidities
  - Documentation of prior treatment trials
  - Sleep study report (if OSA indication)
  - Cardiac history documentation (if CV indication)

Plantillas educativas únicamente. No constituyen asesoramiento legal ni médico. Las cartas deben ser firmadas por el clínico tratante (MD, DO, NP, PA) con autoridad de prescripción. Cada plan cambia los criterios trimestralmente. Verifique con el boletín de política de PA más reciente de su plan antes de enviar. No invente hallazgos clínicos. No altere la firma de un clínico.

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