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Quick verdict
Costco / Success by Sesame is the better pick for most patients on overall scoring. Costco bundles Success by Sesame care with discounted self-pay branded GLP-1 at Costco Pharmacy. The medication price is genuinely low for a brand-name pen: the Wegovy or Ozempic injection is $349/mo self-pay, with care from $59/mo on the annual plan. The catch is a paid Costco membership, and the bundle has no member outcome record yet.
That said, PlushCare wins on specific dimensions. PlushCare is a primary-care telehealth platform that happens to prescribe GLP-1s, not a GLP-1 specialist. That distinction makes it the strongest pick for the insured and the most expensive for everyone else.
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Side-by-side
| PlushCare | Costco / Success by Sesame | |
|---|---|---|
| Starts from | $19.99/mo (+ med separate) | $408/mo (incl. medication) |
| Monthly cost gap | Costco / Success by Sesame is $340/mo cheaper than PlushCare | |
| Lock-in | Month-to-month | Month-to-month |
| Time to prescription | 1 day | 2 days |
| Consultation type | Live | Video |
| Affiliate network | Impact | CJ |
Score by dimension
Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.
| PlushCare | Costco / Success by Sesame | |
|---|---|---|
| Pricing transparency | 5/10 | 7/10 |
| Cancellation terms | 7/10 | 8/10 |
| Onboarding experience | 9/10 | 7/10 |
| Medication options | 7/10 | 7/10 |
| Member reviews | 6.8/10 | 9/10 |
When to choose PlushCare
Best for insurance-covered branded
Patients with commercial insurance that covers Wegovy or Zepbound. PlushCare's PCPs handle prior authorization paperwork well.
PlushCare wins on onboarding experience on the dimensional scoring. The caveat: Cash-pay patients comparing on monthly cost. The membership + visit fees + cash medication math is rarely competitive against specialists.
When to choose Costco / Success by Sesame
Best for Costco members
Existing Costco members who want discounted self-pay branded GLP-1 with light telehealth care attached.
Costco / Success by Sesame wins on pricing transparency, cancellation terms, member reviews and runs $340/mo cheaper than PlushCare at the entry tier ($208 vs $548). Over a year that's $4,080 you keep. The caveat: Anyone who is not a Costco member, wants a compounded option, or wants a long member-review track record.
If cost is your main filter
Costco / Success by Sesame is the cheaper monthly: $208 all-in vs $548 for PlushCare. That's $340 a month or $4,080a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $1020 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.
If lock-in is your main filter
PlushCare (month-to-month) and Costco / Success by Sesame (month-to-month) sit at the same cancellation tier. Read both cancellation policies directly before signing; the on-page summary covers the headline but not the deletion-of-account or refund-window edge cases.
FAQ
Is PlushCare cheaper than Costco / Success by Sesame?
Can I switch from PlushCare to Costco / Success by Sesame mid-treatment?
Which program has better member feedback?
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