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Quick verdict
Costco / Success by Sesame is the better pick for most patients on overall scoring. Costco bundles Success by Sesame care with discounted self-pay branded GLP-1 at Costco Pharmacy. The medication price is genuinely low for a brand-name pen: the Wegovy or Ozempic injection is $349/mo self-pay, with care from $59/mo on the annual plan. The catch is a paid Costco membership, and the bundle has no member outcome record yet.
That said, Calibrate wins on specific dimensions. Calibrate is a coaching and insurance-navigation program whose value proposition has weakened as direct-to-consumer pricing from Lilly and Novo undercut the 'we'll handle insurance for you' pitch. Cut its fee from $299 to $199 in 2026.
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Side-by-side
| Calibrate | Costco / Success by Sesame | |
|---|---|---|
| Starts from | $224/mo (incl. medication) | $408/mo (incl. medication) |
| Monthly cost gap | Costco / Success by Sesame is $16/mo cheaper than Calibrate | |
| Lock-in | 3-mo minimum | Month-to-month |
| Time to prescription | 14 days | 2 days |
| Consultation type | Live | Video |
| Affiliate network | Impact | CJ |
Score by dimension
Scores out of 10, equal-weighted across five dimensions. How we score. The winner of each dimension is highlighted.
| Calibrate | Costco / Success by Sesame | |
|---|---|---|
| Pricing transparency | 5/10 | 7/10 |
| Cancellation terms | 6/10 | 8/10 |
| Onboarding experience | 4/10 | 7/10 |
| Medication options | 7/10 | 7/10 |
| Member reviews | 9.2/10 | 9/10 |
When to choose Calibrate
Best for committed behavioral coaching
Patients who specifically want behavioral coaching and have insurance that covers branded GLP-1s. Calibrate's clinicians and coaches handle prior authorization paperwork well.
Calibrate wins on member reviews on the dimensional scoring. The caveat: Cash-pay patients. With $597 upfront plus $199/mo plus medication separate, the all-in is rarely under $400/mo. Direct LillyDirect or NovoCare paths beat this on price. Note also: Restructured in 2024 amid demand declines
When to choose Costco / Success by Sesame
Best for Costco members
Existing Costco members who want discounted self-pay branded GLP-1 with light telehealth care attached.
Costco / Success by Sesame wins on pricing transparency, cancellation terms, onboarding experience and runs $16/mo cheaper than Calibrate at the entry tier ($208 vs $224). Over a year that's $192 you keep. The caveat: Anyone who is not a Costco member, wants a compounded option, or wants a long member-review track record.
If cost is your main filter
Costco / Success by Sesame is the cheaper monthly: $208 all-in vs $224 for Calibrate. That's $16 a month or $192a year. The 12-month math matters most if you're planning to maintain on GLP-1 long-term. If you're running a 3-month trial, the $48 delta is small against the cost of stopping early on the wrong dose. Insurance changes the picture: if either program runs prior auth and your plan covers Wegovy or Zepbound, branded with copay can beat both cash-pay totals.
If lock-in is your main filter
Calibrate (3-mo minimum) and Costco / Success by Sesame (month-to-month) sit at different cancellation tiers. If you're first-time on a GLP-1 and unsure how you'll tolerate it, Costco / Success by Sesame's easier cancellation is the safer trial.
FAQ
Is Calibrate cheaper than Costco / Success by Sesame?
Can I switch from Calibrate to Costco / Success by Sesame mid-treatment?
Which program has better member feedback?
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