The short version
UnitedHealthcare commercial plans use OptumRx as the pharmacy benefit manager, and OptumRx's GLP-1 PA review is the most rigorous in the US commercial market in 2026. Patients with UHC EPO and PPO plans need the prescriber to submit the correct comorbidity coding, prior-medication-failure documentation and treatment-plan attestation. Programs that file the standard generic PA template get denied by OptumRx at higher rates than the category average.
What we considered
- In-network with UHC commercial
- Knows OptumRx PA-form specifics
- Handles OptumRx step-therapy correctly
- Coordinates with UHC's M&R cardiovascular indication for Wegovy when applicable
Top pick: Form Health
Form HealthBoard-certified obesity docs. Insurance route $25-$199; cash is the steepest.
Starts From
$299/mo+ medication separateLock-In
Month-to-monthScore
7.6
Form Health has the highest documented UHC/OptumRx approval rate in the chart, because their obesity-medicine specialists understand exactly which boxes OptumRx wants checked.
Read the full Form Health review →
Other strong picks
PlushCarePlushCare is in-network with UHC and handles the OptumRx PA, with higher first-pass success when comorbidity documentation already exists.
Starts From
$19.99/mo+ med separateLock-In
Month-to-monthScore
7.2
KnownwellKnownwell's primary-care model produces the comorbidity documentation OptumRx requires as a side effect of normal workup.
Starts From
Insurance-billed+ med separateLock-In
Month-to-monthScore
7.5
9amHealth9amHealth targets metabolic-syndrome patients where UHC coverage is most reliable.
Starts From
$25/mo+ med separateLock-In
Month-to-monthScore
7.4
Related
Why you can trust GLP ChartSame scoring framework applied to every program. No paid placements. No removal of unfavorable information at advertiser request. Pricing is pulled from each program's public-facing page weekly.