Home›Clinical trials›A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Enrolling now · NCT06948435

A study testing whether a GLP-1 medicine from Lilly, orforglipron, can lower blood pressure.

Who can join
Adults 18+, have high blood pressure.
What you take
orforglipron, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
How long it lasts
The full study runs about 2.4 years; your own time in it is usually shorter.
What you get
The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
Phase Phase 3Sponsor Eli Lilly and CompanyDrug orforglipronClass GLP-1 RASites 28 USEnrollment target 487

What this study is for

Full study title: A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1.

Primary condition: Hypertension. Also studied in: Overweight or Obesity.

Who can join, in detail

Age 18 and up
Sex All

Key inclusion criteria

  • refer to the GZPL master protocol for screening eligibility.

Key exclusion criteria

  • refer to the GZPL master protocol for screening eligibility.

Where this study is enrolling

This trial has 28 US sites across 18 states. Contact the site coordinator directly to start the screening process.

Arizona

  • Elite Clinical Studies, LLC
    Phoenix, Arizona

California

  • Valley Clinical Trials, Inc.
    Covina, California
  • Valley Clinical Trials, Inc.
    Northridge, California

Connecticut

  • Chase Medical Research, LLC
    Waterbury, Connecticut

Florida

  • Excel Medical Clinical Trials
    Boca Raton, Florida
  • Care Access - Brandon
    Brandon, Florida
  • Northeast Research Institute - Downtown Office
    Jacksonville, Florida
  • Peace River Cardiovascular Center
    Port Charlotte, Florida

Hawaii

  • East-West Medical Research Institute
    Honolulu, Hawaii

Maryland

  • Ascension Saint Agnes Heart Care
    Baltimore, Maryland

Massachusetts

  • Lucida Clinical Trials
    New Bedford, Massachusetts

Michigan

  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division
    Troy, Michigan

Missouri

  • StudyMetrix Research
    City of Saint Peters, Missouri

Nevada

  • Excel Clinical Research, LLC
    Las Vegas, Nevada
  • Palm Research Center Sunset
    Las Vegas, Nevada

New York

  • Rochester Clinical Research, LLC
    Rochester, New York

Ohio

  • Remington-Davis, Inc
    Columbus, Ohio
  • PriMED Clinical Research
    Dayton, Ohio

Oregon

  • Advanced Research Institute - Tigard
    Tigard, Oregon

South Carolina

  • Care Access - Mauldin
    Mauldin, South Carolina

Texas

  • Dallas Heart and Vascular Consultants, PA
    Duncanville, Texas
  • Texas Institute of Cardiology, PA
    McKinney, Texas
  • North Hills Family Medicine/North Hills Medical Research
    North Richland Hills, Texas

Utah

  • Advanced Research Institute
    Ogden, Utah

Virginia

  • Carient Heart & Vascular - Manassas
    Manassas, Virginia
  • Health Research of Hampton Roads, Inc.
    Newport News, Virginia
  • National Clinical Research, Inc
    Richmond, Virginia

Washington

  • Eastside Research Associates
    Redmond, Washington

Timeline

Started enrolling: 2025-04-30. Expected completion: 2027-09. Last updated on ClinicalTrials.gov: 2026-04-17.

Official source

We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:

View on ClinicalTrials.gov →

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John Samaras, Founder and editorI started GLP Chart after overpaying for a GLP-1 myself. Based in Austin, Texas. About this site · LinkedIn · Contact
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