A study in people with obesity or overweight.

Recruiting now. Registry record last updated July 31, 2026.

Who can join
Adults 18+, have obesity or are overweight, BMI 27.5+.
What you take
Check ClinicalTrials.gov for this trial's study groups and what each group receives.
How long it lasts
The full study runs about 2 years.
What you get
Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
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Phase Not ApplicableSponsor Texas Tech UniversityDrug tirzepatideClass GLP-1/GIPSites 1 USEnrollment target 27

What this study is for

Primary condition: Obesity & Overweight. Also studied in: Cardiometabolic Health Indicators, Addiction, Eating Disorders, Mental Health.

Full scientific study title: Tirzepatide Impact Assessment Study.

Who can join

Age18 and upSexAnyBMI27.5 or higher

Adults 18+, have obesity or are overweight, BMI 27.5+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Age 18 years or older
  • BMI of 27.5 kg/m2 or higher
  • For GLP-1 RA arm: initiating semaglutide or tirzepatide for weight loss as prescribed by their own medical provider
  • For LS comparator arm: not currently taking a GLP-1 receptor agonist or other weight-loss medication, and no use of weight-loss medication within the past 3 months

Key exclusion criteria

  • Pregnant
  • Breastfeeding
  • Wears a pacemaker or other internal medical device
  • Chronic kidney disease in the past 2 years
  • Active cancer or cancer treatment within the past 6 months

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

Texas1 site
  • Nutrition Metabolic Health Initiative (NMHI)
    Lubbock, Texas
    Shannon Dr. Galyean, PhD+18068342286Shannon.Galyean@ttu.edu

Timeline

Started enrolling: January 2, 2025. Expected completion: December 7, 2026. Last updated on ClinicalTrials.gov: July 31, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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