A study testing whether a GLP-1 and GIP medicine, tirzepatide, can help people with diabetes lose weight.

Recruiting now. Registry record last updated July 24, 2026.

Who can join
Adults 18+, have obesity or are overweight.
What you take
Tirzepatide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
How long it lasts
The study runs about 7 months.
What you get
Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
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Phase Not ApplicableSponsor Ohio State UniversityDrug tirzepatideClass GLP-1/GIPSites 1 USEnrollment target 300

What this study is for

Primary condition: Obesity & Overweight. Also studied in: Diabetes (DM).

Full scientific study title: Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists.

Who can join

Age18 and upSexAny

Adults 18+, have obesity or are overweight. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Adult aged 18 years or older
  • Currently taking a GLP-1 receptor agonist medication
  • On the GLP-1 receptor agonist for at least 3 months
  • Using the GLP-1 receptor agonist for type 2 diabetes, overweight or obesity, and/or weight management (self-reported)
  • Stable GLP-1 receptor agonist dose for the past 4 to 8 weeks

Key exclusion criteria

  • Currently or planning to become pregnant
  • Planned bariatric surgery within the next 3 months
  • Recent bariatric surgery (within the past 3 months) or other conditions that substantially alter resistance training capacity (e.g., advanced cancer cachexia, severe mobility-limiting conditions)
  • Unable to read or respond to the survey in English

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

Ohio1 site
  • The Ohio State University
    Columbus, Ohio
    Madison L Kackley, PhD614-247-9650kackley.19@osu.edu

Timeline

Started enrolling: June 12, 2026. Expected completion: January 2027. Last updated on ClinicalTrials.gov: July 24, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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