A study listed on ClinicalTrials.gov.

Who can join
Adults 18+, have obesity or are overweight.
What you take
Check ClinicalTrials.gov for this trial's study groups and what each group receives.
How long it lasts
The full study runs about 3 years.
What you get
Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
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Phase Not ApplicableSponsor University of Alabama at BirminghamDrug investigational drugClass OtherSites 1 USEnrollment target 64

What this study is for

Primary condition: Weight Loss. Also studied in: GLP - 1, Weight Loss Maintenance, Obesity & Overweight.

Full scientific study title: Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation.

Who can join

Age18 and upSexAny

Adults 18+, have obesity or are overweight. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Age 18 years or older
  • Loss of ≥15% of initial body weight using anti-obesity medication
  • Discontinued anti-obesity medication within the past 4 weeks or planning to discontinue prior to randomization
  • ≤3 kg weight regain within the past 3 months
  • Willing and able to participate in a 6-month behavioral intervention, including a 10-week foundational program

Key exclusion criteria

  • Medical conditions that would preclude safe participation in physical activity, dietary changes, or mind-based practices (e.g., unstable cardiovascular disease, uncontrolled hypertension, severe orthopedic limitations, or seizure disorders not medically managed)
  • Active psychiatric conditions that would interfere with participation or safety (e.g., untreated major depression, active substance use disorder, or psychosis)
  • Pregnancy, breastfeeding, or plans to become pregnant during the study period
  • Current participation in another structured weight loss or weight maintenance program
  • Continued use of anti-obesity medication after randomization

Where this trial runs

This trial has 1 sites across 1 state. Site contacts are listed for reference. They are not screening through this trial right now.

Alabama1 site
  • University of Alabama at Birmingham
    Birmingham, Alabama
    Holly Wyatt, MD205-975-6270drholly@uab.edu

Timeline

Scheduled start: November 1, 2026. Expected completion: July 31, 2029. Last updated on ClinicalTrials.gov: June 26, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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