A study testing whether a new weekly shot from University of Texas Southwestern Medical Center, tirzepatide, works for this condition.
- Who can join
- Adults 18+, have hfpef - heart failure with preserved ejection fraction.
- What you take
- tirzepatide, given as part of the study at no cost to you. Some participants may receive a placebo (an inactive version) instead, decided at random.
- How long it lasts
- The full study runs about 1.8 years; your own time in it is usually shorter.
- What you get
- The study medication and study-related care at no cost. Compensation varies by study site; many cover travel and provide the study medication at no cost. The trial coordinator will explain what that site offers before you join.
What this study is for
Primary condition: HFpEF - Heart Failure With Preserved Ejection Fraction. Also studied in: Diabetic Cardiomyopathies.
Full scientific study title: Tailored Exercise Training Study Among Adults With HFpEF.
Who can join
Adults 18+, have hfpef - heart failure with preserved ejection fraction. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Age>= 18 yrs
- LVEF (Left Ventricular Ejection Fraction) >= 50%
- History of HFpEF or at risk of HFpEF
- HFpEF diagnosis based on:- -HF hospitalization within 12 months-
- NT-proBNP >360 pg/mL
Key exclusion criteria
- Hospitalization 1 month prior to baseline visit
- History of recurrent falls
- eGFR (Estimated Glomerular Filtration Rate) <20ml/min/1.73m
- Active changes in HF therapies over 2 weeks prior to baseline visit
- Inability participate in exercise training therapy
Where this study is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Texas1 site
- University of Texas Southwestern Medical CenterDallas, Texas
Timeline
Started enrolling: 2025-02-18. Expected completion: 2026-12-30. Last updated on ClinicalTrials.gov: 2025-10-31.
Official source
We sync this data quarterly from ClinicalTrials.gov, the federal registry for clinical research. Before contacting a site, verify the trial is still recruiting on the official page:
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