A study testing whether a GLP-1 and GIP medicine, tirzepatide, affects healthy aging.
Recruiting now. Registry record last updated March 24, 2026.
- Who can join
- Adults 55 to 70, have aging, BMI 27+.
- What you take
- Tirzepatide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
- How long it lasts
- The full study runs about 2 years.
- What you get
- Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
What this study is for
Primary condition: Aging. Also studied in: LONGEVITY 1.
Full scientific study title: Tirzepatide to Slow Biological Aging.
Who can join
Adults 55 to 70, have aging, BMI 27+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Age 55-70 years
- BMI ≥ 30 kg/m² or ≥ 27 kg/m² if also with ≥ 1 weight-related comorbidity
- If taking anti-inflammatory or blood-pressure-/lipid-/glucose-lowering medications, no change in dose for ≥12 weeks prior to entry and no plans to dose escalate for the study duration
- Willing and able to provide written informed consent and undergo all required study procedures
Key exclusion criteria
- BMI \>35 kg/m²
- Uncontrolled or end-stage, comorbid, cardiometabolic disease, in the opinion of the site investigator
- Significant neurocognitive impairment, in the opinion of the site investigator
- Current or planned use of medications for the treatment of obesity, or medications likely to cause significant changes in weight, during the study period (see prohibited medications, section 6.0)
- Use of insulin
Where this trial is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Texas1 site
- University of Texas Medical BranchGalveston, Texas
Timeline
Started enrolling: February 27, 2026. Expected completion: January 2028. Last updated on ClinicalTrials.gov: March 24, 2026.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:
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