A study of a study medicine in people with loose skin.
- Who can join
- Adults 25 to 65, women only, have loose skin.
- What you take
- Check ClinicalTrials.gov for this trial's study groups and what each group receives.
- How long it lasts
- The study runs about 12 months.
- What you get
- Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
What this study is for
Primary condition: Laxity; Skin.
Full scientific study title: Assess Impact of Poly-L-lactic Acid on GLP1 Subjects.
Who can join
Adults 25 to 65, women only, have loose skin. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Adult women aged 25-65 years.
- Fitzpatrick skin types I-IV.
- Presence of mild to moderate skin laxity of abdomen, as determined by clinical investigators.
- Stable weight for 3 months, with body mass index (BMI) of 27 or less.
- Current treatment with a stable dose of GLP-1 agonist medication for at least the last 6 months, for 15 of the enrolled subjects. Remaining 5 subjects should not be taking or have a history of taking a GLP-1 agonist medication, and should not be planning to take a GLP-1 in the foreseeable future.
Key exclusion criteria
- The presence of severe abdominal skin laxity as determined by clinical investigators.
- Still actively losing weight.
- Pregnancy or planned pregnancy during the study or currently breastfeeding.
- Any uncontrolled systemic disease.
- History of autoimmune connective tissue disease.
Where this trial runs
This trial has 1 sites across 1 state. Site contacts are listed for reference. They are not screening through this trial right now.
California1 site
- West Dermatology Research CenterSan Diego, California
Timeline
Scheduled start: October 27, 2025. Expected completion: October 31, 2026. Last updated on ClinicalTrials.gov: October 16, 2025.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:
Other GLP-1 clinical trials
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