A study in people with prediabetes.

Recruiting now. Registry record last updated October 7, 2025.

Who can join: Adults 35 to 65, have prediabetes, BMI 25+.
What you take: Check ClinicalTrials.gov for this trial's study groups and what each group receives.
How long it lasts: The study runs about 7 months.
What you get: Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.

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Phase Not ApplicableSponsor Nanjing Nutrabuilding Bio-tech Co., Ltd.Drug investigational drugClass OtherSites 1 USEnrollment target 54

What this study is for

Primary condition: Prediabetes.

Full scientific study title: Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes.

Who can join

Age35 to 65SexAnyBMI25 to 35

Adults 35 to 65, have prediabetes, BMI 25+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key exclusion criteria

Extreme Diets: Extreme dietary habits (e.g., ketogenic, vegan/vegetarian) at investigator's discretion.
Intense Exercise: Moderate-to-intense physical training (≥5 hours/week).
Weight Instability/Program: Recent weight changes (\>4.5 kg≤90 d) or current/planned weight change program.
Abnormal Labs: Abnormal lab test results of clinical significance at Visit 1 (one re-test allowed).
Uncontrolled Chronic Illness: Uncontrolled or clinically important pulmonary, cardiac, hepatic, renal, endocrine (T1D/T2D excluded), hematologic, immunologic, neurologic, psychiatric, or biliary disorders.

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

Illinois1 site

Merieux NutriSciences
Addison, Illinois
Elizabeth Antoo, MD(630) 617-2000elizabeth.antoo@mxns.com

Follow this trial

We email you if NCT07210684 changes status, adds new sites in your state, or if a similar trial opens for the same condition.

Timeline

Started enrolling: August 6, 2025. Expected completion: March 15, 2026. Last updated on ClinicalTrials.gov: October 7, 2025.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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John Samaras, Founder and EditorI started GLP Chart after overpaying for a GLP-1 myself. Based in Austin, Texas.
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