A study testing whether a GLP-1 medicine can help people ease psoriatic arthritis.

Recruiting now. Registry record last updated August 10, 2026.

Who can join
Adults 18+, have psoriatic arthritis.
What you take
Check ClinicalTrials.gov for this trial's study groups and what each group receives.
How long it lasts
The full study runs about 2 years.
What you get
Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
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Phase Phase 4Sponsor Medical College of WisconsinDrug GLP-1 agonistsClass OtherSites 1 USEnrollment target 22

What this study is for

Primary condition: Psoriatic Arthritis (PsA).

Full scientific study title: Impact of Glucagon-like Peptide-1 (GLP-1) Analogs on Disease Outcomes in Psoriatic Arthritis: A Pragmatic Randomized Controlled Trial.

Who can join

Age18 and upSexAny

Adults 18+, have psoriatic arthritis. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Adult patients (age 18 and older) who present to rheumatology clinic
  • Participants must be able to read, understand, and provide documented informed consent as approved by the Institutional Review Board (IRB).
  • Meet the Classification of Psoriatic Arthritis (CASPAR) criteria for PsA
  • Participants must have a Body Mass Index (BMI) of 30 kg/m\^2
  • Participants must be treated for PsA in accordance with guidelines

Key exclusion criteria

  • Any prior use of GLP-1 agonists
  • Inability to provide informed consent
  • Current participation in another PsA study
  • Treatment initiation by GLP-1 agonists contraindicated by FDA
  • Patients with hemoglobin A1c (HbA1c) \> 10 at baseline

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

Wisconsin1 site
  • Medical College of Wisconsin/Froedtert Hosptial
    Milwaukee, Wisconsin
    Shikha Singla, MD414-955-7040ssingla@mcw.edu

Timeline

Started enrolling: May 1, 2026. Expected completion: October 15, 2028. Last updated on ClinicalTrials.gov: August 10, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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