A study testing whether a GLP-1 medicine, liraglutide, can help people with maturity-onset diabetes of the young (MODY) lower blood sugar.

Recruiting now. Registry record last updated December 17, 2025.

Who can join
Ages 10+, have maturity-onset diabetes of the young (MODY), BMI 18.5+.
What you take
Liraglutide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
How long it lasts
The full study runs about 2 years.
What you get
Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
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Phase Phase 2Sponsor MansaDrug liraglutideClass GLP-1 RASites 1 USEnrollment target 50

What this study is for

Primary condition: Maturity Onset Diabetes of the Young.

Full scientific study title: Liraglutide Treatment in Patients With Maturity-onset Diabetes of the Young (MODY).

Who can join

Age10 and upSexAnyBMI18.5 or higher

Ages 10+, have maturity-onset diabetes of the young (MODY), BMI 18.5+. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

  • Diagnosis of MODY via genetic testing
  • HgbA1c \>6.5%

Key exclusion criteria

  • History of anaphylaxis to GLP-1 receptor agonists
  • Already taking GLP-1 receptor agonists
  • on medications within the stimulant class
  • have had bariatric surgery
  • personal or family history of cancer, especially medullary thyroid cancer

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

Ohio1 site
  • Cincinnati Children's Hospital Medical Center
    Cincinnati, Ohio
    Lily Deng513-636-0002lily.deng@cchmc.org

Timeline

Started enrolling: May 8, 2025. Expected completion: January 2027. Last updated on ClinicalTrials.gov: December 17, 2025.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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