A study testing whether a GLP-1 medicine, semaglutide, can help people lose weight.
- Who can join
- Children and teens 12 to 18, have obesity.
- What you take
- Semaglutide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
- How long it lasts
- The full study runs about 5 years.
- What you get
- Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
What this study is for
Primary condition: Obesity, Childhood.
Full scientific study title: GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward.
Who can join
Children and teens 12 to 18, have obesity. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Aged 12 to \< 18 years at screening
- BMI \>/= 95th percentile based on age and sex at screening
- Provide release of information for established primary health provider
- Own a device capable of connecting to the virtual platform sessions with video
Key exclusion criteria
- Diabetes (type 1 or 2) due to safety concerns about proper surveillance of glycemic control virtually
- HbA1c \>/= 6.5%
- Current or recent (\< 6 months prior to screening) use of FDA-approved obesity medications
- Previous metabolic/bariatric surgery or metabolic/bariatric surgery planned during the study period
- Hypertriglyceridemia (TG \>/= 500 mg/dL)
Where this trial runs
This trial has 1 sites across 1 state. Site contacts are listed for reference. They are not screening through this trial right now.
Minnesota1 site
- University of Minnesota, Center for Pediatric Obesity MedicineMinneapolis, Minnesota
Timeline
Scheduled start: October 1, 2026. Expected completion: January 31, 2032. Last updated on ClinicalTrials.gov: June 16, 2026.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:
Other GLP-1 clinical trials
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