A study testing whether a study medicine can help people with type 2 diabetes lower blood sugar.

Who can join: Adults 25 to 70, have type 2 diabetes.
What you take: Check ClinicalTrials.gov for this trial's study groups and what each group receives.
How long it lasts: The full study runs about 2 years.
What you get: Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.

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Phase Phase 2Sponsor Mayo ClinicDrug investigational drugClass OtherSites 1 USEnrollment target 80

What this study is for

Primary condition: Genetic Predisposition. Also studied in: Type2diabetes.

Full scientific study title: The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans.

Who can join

Age25 to 70SexAny

Adults 25 to 70, have type 2 diabetes. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

Subjects with the TT or CC genotype at rs7903146

Key exclusion criteria

Age \< 25 or \> 70 years (to avoid studying subjects who could have latent type 1 diabetes, or the effects of age extremes in subjects with normal or impaired fasting glucose).
CT genotype at rs7903146
HbA1c \> 6.5%
Use of any glucose-lowering agents including metformin or sulfonylureas.
For female subjects: positive pregnancy test at the time of enrollment or study.

Where this trial runs

This trial has 1 sites across 1 state. Site contacts are listed for reference. They are not screening through this trial right now.

Minnesota1 site

Mayo Clinic in Rochester
Rochester, Minnesota

Follow this trial

We email you if NCT06972407 changes status, adds new sites in your state, or if a similar trial opens for the same condition.

Timeline

Scheduled start: October 1, 2026. Expected completion: March 1, 2029. Last updated on ClinicalTrials.gov: January 30, 2026.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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John Samaras, Founder and EditorI started GLP Chart after overpaying for a GLP-1 myself. Based in Austin, Texas.
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