A study testing whether a GLP-1 medicine, semaglutide, can help people lose weight.

Recruiting now. Registry record last updated May 11, 2025.

Who can join: Adults 18+, have obesity.
What you take: Semaglutide, given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
How long it lasts: The full study runs about 3 years.
What you get: Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.

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Phase Not ApplicableSponsor University of California, Los AngelesDrug semaglutideClass GLP-1 RASites 1 USEnrollment target 20

What this study is for

Primary condition: Obesity.

Full scientific study title: Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects..

Who can join

Age18 and upSexAny

Adults 18+, have obesity. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

Subjects scheduled to start semaglutide for weight loss (drug not provided by or paid for by the study)
\>18 years of age and willing to participate
Male or post-menopausal females

Key exclusion criteria

History of prior neck surgery and /or neck irradiation
Use of beta blocker agents
Use of any other glucose lowering medication
History of neuropathic disorders (e.g. diabetic neuropathy)
Diabetic patients

Where this trial is enrolling

This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.

California1 site

UCLA Health
Los Angeles, California
Julie Sorg, MSNjsorg@mednet.ucla.edu

Follow this trial

We email you if NCT05419726 changes status, adds new sites in your state, or if a similar trial opens for the same condition.

Timeline

Started enrolling: February 1, 2023. Expected completion: February 1, 2026. Last updated on ClinicalTrials.gov: May 11, 2025.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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John Samaras, Founder and EditorI started GLP Chart after overpaying for a GLP-1 myself. Based in Austin, Texas.
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