A study of a study medicine, Exendin-(9-39).

Recruiting now. Registry record last updated September 9, 2025.

Who can join: Adults 18 to 65.
What you take: Exendin-(9-39), given as part of the study. Check ClinicalTrials.gov for this trial's study groups, including any placebo or comparison medicine.
How long it lasts: The full study runs about 12 years.
What you get: Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.

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Phase Phase 1Sponsor The University of Texas Health Science Center at San AntonioDrug Exendin-(9-39)Class OtherSites 2 USEnrollment target 200

What this study is for

Primary condition: Post Bariatric Surgery. Also studied in: Gastric Bypass, Sleeve Gastrectomy, Hypoglycemia After Gastric Bypass.

Full scientific study title: The Effects of Bariatric Surgeries on Glucose Metabolism.

Who can join

Age18 to 65SexAny

Adults 18 to 65. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.

Full medical eligibility (for you and your doctor)verbatim from the registry

This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.

Key inclusion criteria

Hypoglycemic RYGB patients with documented blood glucose level \<50 mg/dl
Asymptomatic individuals with bariatric surgery
Healthy non-surgical patients with no personal history of diabetes
Subjects must physically be able to come to our clinical research center Cedars-Sinai Medical Center

Key exclusion criteria

Active heart, lung, liver, gastrointestinal or kidney disease; unable to give informed consent; pregnancy; uncontrolled high blood pressure or high cholesterol; significant anemia (hemoglobin \<11g/dL); prisoners or institutionalized individuals; type 2 diabetes mellitis; development of any serious medical or psychiatric illness during recruitment or studies;
RYGB patients will be disqualified if they have gastric outlet obstruction or severe diarrhea.
Healthy non-surgical patients with personal history of diabetes
History of glaucoma
Uncontrolled hypertension (any subjects with BP\>140/90 and history of dyslipidemia

Where this trial is enrolling

This trial has 2 sites across 1 state. Contact a site coordinator directly to start screening.

Texas2 sites

Texas Diabetes Institute - University Health System
San Antonio, Texas
Marzieh Salehi, MD210-567-6691hansisdiarte@uthscsa.edu
South Texas Veterans Health Care System
San Antonio, Texas
Marzieh Salehi, MD210-567-6691salehi@uthscsa.edu

Follow this trial

We email you if NCT02823665 changes status, adds new sites in your state, or if a similar trial opens for the same condition.

Timeline

Started enrolling: July 2015. Expected completion: August 2027. Last updated on ClinicalTrials.gov: September 9, 2025.

Official source

Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:

View on ClinicalTrials.gov →

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