A study in people with cystic fibrosis.
Recruiting now. Registry record last updated January 14, 2026.
- Who can join
- Adults 18+, have cystic fibrosis.
- What you take
- Check ClinicalTrials.gov for this trial's study groups and what each group receives.
- How long it lasts
- The full study runs about 14 years.
- What you get
- Costs vary by study. Ask the study team what this one covers, including the study medicine, visits and travel, before you sign the consent form.
What this study is for
Primary condition: Cystic Fibrosis. Also studied in: Pancreatic Insufficiency.
Full scientific study title: Beta-cell Response to Incretin Hormones in Cystic Fibrosis.
Who can join
Adults 18+, have cystic fibrosis. A site coordinator confirms whether you qualify during a free screening visit. The exact medical requirements are below.
Full medical eligibility (for you and your doctor)verbatim from the registry
This is the exact wording from ClinicalTrials.gov, including clinical measures (lab values, imaging scores). Bring it to your doctor if any of it is unclear.
Key inclusion criteria
- Confirmed diagnosis of cystic fibrosis, defined by positive sweat test or CFTR mutation analysis according to CFF diagnostic criteria,
- Age greater than or equal to 18y on date of consent
- Pancreatic insufficiency
- Recent OGTT consistent with Indeterminate-GT, IGT, CFRD w/o fasting hyperglycemia, or an established diagnosis of CFRD without fasting hyperglycemia
- For female subjects, negative urine pregnancy test at enrollment.
Key exclusion criteria
- Established diagnosis of non-CF diabetes (i.e. T1D) or CFRD with fasting hyperglycemia (fasting glucose greater than126 mg/dL)
- History of clinically symptomatic pancreatitis within last year
- Prior lung or liver transplant
- Severe CF liver disease, as defined by portal hypertension
- Fundoplication-related dumping syndrome
Where this trial is enrolling
This trial has 1 sites across 1 state. Contact a site coordinator directly to start screening.
Pennsylvania1 site
- Children's Hospital of Philadelphia and University of PennsylvaniaPhiladelphia, Pennsylvania
Timeline
Started enrolling: May 2013. Expected completion: December 2026. Last updated on ClinicalTrials.gov: January 14, 2026.
Official source
Every Monday we check this trial against ClinicalTrials.gov, the federal registry for clinical research. Last checked September 4, 2026. Confirm the current status there before you contact a site:
Other GLP-1 clinical trials
Back to the full directory → or take the matching quiz if you want clinical trials filtered to your conditions and location.
